成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

MRK 560

MRK 560 Struktur
677772-84-8
CAS-Nr.
677772-84-8
Englisch Name:
MRK 560
Synonyma:
MRK 560;MRK-560; MRK560;WDZVWDXOIGQJIO-UJKQEGAGSA-N;N-[cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide;Methanesulfonamide, N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoro-;N-((1s,4s)-4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)-1,1,1-trifluoromethanesulfonamide;MRK-560,Jurkat cells,DND-41,Aβ peptides,MRK560,MRK 560,Gamma secretase,γ-secretase,T-ALL,Inhibitor,inhibit,Alzheimer’s disease,HPB-ALL
CBNumber:
CB02538282
Summenformel:
C19H17ClF5NO4S2
Molgewicht:
517.92
MOL-Datei:
677772-84-8.mol

MRK 560 Eigenschaften

Siedepunkt:
580.1±60.0 °C(Predicted)
Dichte
1.57±0.1 g/cm3(Predicted)
storage temp. 
Store at 4°C
L?slichkeit
<51.79mg/ml in DMSO; <25.9mg/ml in ethanol
Aggregatzustand
solid
pka
5.97±0.40(Predicted)
Farbe
White

Sicherheit

MRK 560 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

MRK-560 is a potent inhibitor of γ-secretase (IC50 = 0.65 nM). In vivo, MRK-560 (1-10 mg/kg) reduces diethanolamine-soluble amyloid-β (1-40) (Aβ40) levels in APP-YAC transgenic mouse brain. MRK-560 reduces brain and cerebrospinal fluid Aβ40 levels in rats (ED50s = 6 and 10 mg/kg, respectively). It also decreases brain-soluble Aβ40 and Aβ42 levels and recovers hippocampal long-term potentiation in the Tg2576 transgenic mouse model of Alzheimer''s disease.

Verwenden

MRK 560 acts as a y-secretase inhibitor that is orally bioavailable and potent and may be used in a therapeutic strategy to counter low amyloid (β) production in Alheimer’s disease.

MRK 560 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

MRK 560 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 38)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185
 sales-cpd@caerulumpharma.com China 3466 58
Shanghai Beckham Medical Technology Co., Ltd 021-13816613772 13816613772
 huahero21@sina.com China 652 55
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
 2853530910@QQ.com China 8011 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
 sales@rechemscience.com China 2999 58
Shanghai zhigan biotechnology co., LTD
zhiqianbio@126.com China 19778 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
  • N-[cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide
  • N-((1s,4s)-4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)-1,1,1-trifluoromethanesulfonamide
  • MRK 560
  • Methanesulfonamide, N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoro-
  • MRK-560; MRK560
  • WDZVWDXOIGQJIO-UJKQEGAGSA-N
  • MRK-560,Jurkat cells,DND-41,Aβ peptides,MRK560,MRK 560,Gamma secretase,γ-secretase,T-ALL,Inhibitor,inhibit,Alzheimer’s disease,HPB-ALL
  • 677772-84-8
  • C19H17ClF5NO4S2
Copyright 2019 ? ChemicalBook. All rights reserved