BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P333+P313
Bei Hautreizung oder -ausschlag: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
An enzyme that is located in catecholamine-synthesizing cells and is responsible
for the hydroxylation of L-tyrosine to L 3,4-dihydroxyphenylalanine (L-dopa). This is the initial and rate-limiting step in the biosynthetic pathway for catecholamines (dopamine, norepinephrine, and epinephrine). In addition to hydroxylating tyrosine using biopterin as a coenzyme, this enzyme can also
hydroxylate phenylalanine to tyrosine. The enzyme is located in the cytosol of catecholamine neurons and has a Km for tyrosine that is in the micromolar range.
Verwenden
Anti-th antibody produced in rabbit has been used in:
western blotting (1:1000)
whole retinal flat-mount immunolabelling (1:500)
immunofluorescence (2:1000)
immunohistochemistry (2:1000)
Allgemeine Beschreibung
Tyrosine hydroxylase?(TH) is a cytoplasmic enzyme. The TH gene codes for a monooxygenase.