ANTI-MDM2
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- CAS-Nr.
- Englisch Name:
- ANTI-MDM2
- Synonyma:
- MDMX;HDMX;HDM2;MGC5370;MGC71221;Anti-HDM4;ANTI-MDM4;ANTI-MDM2;ANTI-HDMX;Anti-hdm2
- CBNumber:
- CB0241012
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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ANTI-MDM2 Eigenschaften
- storage temp.
- −20°C
- Aggregatzustand
- buffered aqueous solution
ANTI-MDM2 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Monoclonal Anti-MDMX antibody is suitable for use in immunocytochemistry, immunoprecipitation, immunoblot (approx. 80 kDa), microarray, and ELISA. The product may also be used for western blot and for assessing ectopic expression of MDMX (using a conc. of 1-2 μg/mL in total cell extract of HEK 293T cells transfected with human MDMX).
Allgemeine Beschreibung
Monoclonal Anti-MDMDX (mouse IgG1 isotype) is derived from the hybridoma MDMX-82 produced by the fusion of mouse myeloma cells (NS1 cells) and splenocytes from BALB/c mice. MDMX belongs to the MDM family. The MDMX/ mouse double minute 4 (MDM4) gene encode a 490 amino acid protein. MDMX comprises a putative nuclear localization signal, a really interesting new gene (RING) finger domain in the C terminal and a p53-binding domain in the N terminal. MDMX has significant structural similarity to MDM2 E3 ubiquitin ligase.
Biochem/physiol Actions
MDMX is a structural homolog of MDM2 and inhibits the tumor suppressor, p53. MDMX also prevents MDM2-mediated degradation of p53, and subsequently regulates cellular levels of p53. MDMX also modulates cell growth and survival. Thus, MDMX can be useful as a therapeutic target in cancers, especially in tumors where native p53 functions can be restored . Monoclonal Anti-MDMX antibody is specific for human MDMX.
ANTI-MDM2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI-MDM2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 30)Lieferanten
- ANTI-UBIQUITIN PROTEIN LIGASE
- ANTI-UBIQUITIN PROTEIN LIGASE (AB-1), HUMAN
- p53-binding protein Mdm2
- Ubiquitin-protein ligase E3 Mdm2
- double minute 4 protein
- Mdm2-like p53-binding protein
- MDMX
- p53-binding protein Mdm4
- Anti-Double minute 4 protein
- Anti-Mdm2-like p53-binding protein
- Anti-MDM4 antibody produced in rabbit
- Anti-p53-binding protein Mdm4
- Anti-Protein Mdm4
- Anti-Protein Mdmx
- Anti-HGNC:6973
- Anti-MDM2 (Isoform) antibody produced in goat
- Anti-Transformed 3T3 cell double minute 2
- Anti-MDM2 (Ab-166) antibody produced in rabbit
- Anti-hdm2 antibody produced in rabbit
- Anti-HDMX antibody produced in rabbit
- Anti-Mdm2 p53 binding protein homolog (mouse) antibody produced in rabbit
- Anti-MGC71221 antibody produced in rabbit
- Anti-phospho-MDM2 (pSer166) antibody produced in rabbit
- Anti-Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)
- HDMX
- MDM2, untagged human
- MGC5370
- MGC71221
- Anti-MDM2 antibody produced in chicken
- Anti-Mouse double minute 2 homolog isoform MDM2
- Anti-Ubiquitin-protein ligase E3 Mdm2
- Anti-MDM2, C-Terminal antibody produced in rabbit
- Anti-HDM4
- Anti-MGC132766
- ANTI-UBIQUITIN PROTEIN LIGASE (AB-1) MOUSE MAB
- ANTI-UBIQUITIN PROTEIN LIGASE (AB-2), HUMAN
- ANTI-UBIQUITIN PROTEIN LIGASE (AB-2) MOUSE MAB
- ANTI-MDM4
- ANTI-MDM2(C-18)
- ANTI-MDM2(N-20)
- ANTI-MDM2 PROTEIN
- ANTI-MDM2
- ANTI-MDM2 (AB-1)
- ANTI-MDM2 (AB-1), HUMAN
- ANTI-MDM2 (AB-1) MOUSE MAB
- ANTI-MDM2 (AB-2)
- ANTI-MDM2 (AB-2), HUMAN
- ANTI-MDM2 (AB-2) MOUSE MAB
- ANTI-MURINE DOUBLE MINUTE 2
- ANTI-MURINE DOUBLE MINUTE CHROMOSOME-2 (AB-1) MOUSE MAB
- ANTI-MURINE DOUBLE MINUTE CHROMOSOME 2 (AB-2)
- ANTI-P53 BINDING PROTEIN
- ANTI-P53 BINDING PROTEIN (AB-1), HUMAN
- ANTI-P53 BINDING PROTEIN (AB-1) MOUSE MAB
- ANTI-P53 BINDING PROTEIN (AB-2), HUMAN
- ANTI-P53 BINDING PROTEIN (AB-2) MOUSE MAB
- ANTI-ONCOPROTEIN MDM-2
- ANTI-ONCOPROTEIN MDM-2, MOUSE
