Rutaecarpine
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Rutaecarpine Eigenschaften
- Schmelzpunkt:
- 259.5-260°
- Siedepunkt:
- 429.62°C (rough estimate)
- Dichte
- 1.2030 (rough estimate)
- Brechungsindex
- 1.5855 (estimate)
- storage temp.
- Sealed in dry,2-8°C
- L?slichkeit
- DMSO: 18 mg/mL clear yellow solution, soluble
- Aggregatzustand
- solid
- pka
- 15.79±0.20(Predicted)
- Farbe
- white
- Merck
- 14,8298
- InChIKey
- ACVGWSKVRYFWRP-UHFFFAOYSA-N
- CAS Datenbank
- 84-26-4(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | T | ||
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R-S?tze: | 25-36/37/38 | ||
S-S?tze: | 45-36-26 | ||
RIDADR | UN 2811 6.1/PG 3 | ||
WGK Germany | 3 | ||
RTECS-Nr. | NM3454000 | ||
HS Code | 29339900 |
Bildanzeige (GHS) | |||||||||||||||
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Alarmwort | Warnung | ||||||||||||||
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Rutaecarpine Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R25:Giftig beim Verschlucken.S-S?tze Betriebsanweisung:
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).Beschreibung
This alkaloid occurs with Evodiamine (q.v.) in the Chinese drug 'Wou-chou-yu' which is the dried fruit of Evodia rutaecarpa Benth. It crystallizes from boiling EtOH as colourless, or pale yellow, needles and is optically inactive. The acetyl derivative has m.p. 184-6°C and the benzoyl compound, m.p. 194°C. The alkaloid gives a yellow colour with concentrated H2S04 and is decomposed by KOH in boiling amyl alcohol yielding anthranilic acid and 3-{3-aminoethylindole- 2-O!carboxylic acid, CllH120 2N2, silky crystals, m.p. 257°C.Pharmacologically, the alkaloid causes increased arterial pressure on injection.
Chemische Eigenschaften
SolidVerwenden
Rutaecarpine is an indole alkaloid contained in the fruit of Evodiae fruits. It been shown to ameliorate bodyweight gain through orexigenic neuropeptides NPY and AgRP. It also playes a role in the treatment of high blood pressureEinzelnachweise
Asahina, Kashiwagi., J. Pharm. Chim., 14,54 (1916)Asahina, Mayeda.,J. Pharm. Soc., Japan, No. 416 (1916)
Asahina, Fujita., ibid, 863 (1921)
Kermack, Perkin, Robinson.,J. Chem. Soc., 119,1615 (1921)
Asahina, Manske, Robinson., ibid, 1708 (1927)
Asahina, Irie, Ohta., J. Pharm. Soc., Japan, 48, 51 (1928)
Ohta., ibid, 60, 109 (1940)
Schopf, Steuer., Annalen, 558, 124 (1947)
Biosynthesis:
Yamazaki, Ikuta., Tetrahedron Lett., 3221 (1966)
Yamazakietal., ibid, 3317 (1967)
Pharmacology:
Raymond-Hamet., Cornpt. rend., 220, 749 (1945)
Rutaecarpine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Rutaecarpine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 335)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 997 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 |
sales@capot.com | China | 29793 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21634 | 55 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 |
FandaChem@Gmail.com | China | 8778 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3009 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32956 | 60 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3619 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29880 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3772 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
84-26-4()Verwandte Suche:
Hydroxyevodiamine
Evodiamine
Bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-8,8'-diapo-.psi.,.psi.-carotindioat
Rutosid
Stigmasta-5,22-dien-3-β-ol
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyron
- :3,4]pyrido[2,1-b]quinazolin-5(7H)-one
- Indolo(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13-dihydro- (9CI)
- Rutecarpine (8CI)
- 7,8-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
- RHETINE
- 8,13-DIHYDRO-INDOLO[2'3':3,4]PYRIDO[2,1-B]QUINAZOLIN-5(7H)-ONE
- RUTECARPINE 95+
- Rutaecarpine std.
- Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one,8,13-dihydro-
- Rutecarpine, 8,13-Dihydroindolo[2μ,3μ:3,4]pyrido[2,1-b]quinazolin-5(7H)-one
- 5,7,8,13-Tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazoline-5-one
- Rutaecarpine (Rutecarpine)
- Rutaecarpine
- Rutaecarpine (synthetic)
- Rutaecarpine, froM TetradiuM ruticarpuM
- Rutaecarpine, 98%, from Evodia rutaecarpa (Juss.) Benth.
- Rutaecarpine 84-26-4
- Rutaecarpine >
- Rutaecarpine USP/EP/BP
- Rutaccarpine
- Rutacarpine
- RUTECARPINE
- Rutaecarpine 98%min
- 7,8-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
- Rutaecarpine-RM
- Rutaecarpine, Indoloquinazoline alkaloid
- Wu Zhuyu alkaloid
- 84-26-4
- 84-16-4
- Cell Signaling and Neuroscience
- Ion Channels
- Monovalent Ion Channels
- Potassium Channel Modulators
- Voltage-gated Ion Channels
- BioChemical
- Cell Biology
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Indoles and derivatives
- Inhibitors