(5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER
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- CAS-Nr.
- 914349-79-4
- Englisch Name:
- (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER
- Synonyma:
- 2-Bromo-5-(boc-amino)pyrazine;N-Boc-2-Amino-5-bromopyrazine;2-(Boc-amino)-5-bromopyrazine;2-Amino-5-bromopyrazine, 2-BOC;tert-Butyl (5-bromopyrazin-2-yl);2-Amino-5-bromopyrazine, 2-BOC protected;2-Amino-5-bromopyrazine, 2-BOC protected 98%;(5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER;(5-BROMOPYRAZINYL)CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER;CarbaMicacid,(5-broMopyrazinyl)-,1,1-diMethylethylester
- CBNumber:
- CB0179285
- Summenformel:
- C9H12BrN3O2
- Molgewicht:
- 274.11
- MOL-Datei:
- 914349-79-4.mol
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(5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Eigenschaften
- Siedepunkt:
- 295.2±40.0 °C(Predicted)
- Dichte
- 1.513±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 10.75±0.70(Predicted)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| HS Code |
2933998090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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(5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
(5-BROMOPYRAZIN-2-YL) CARBAMIC ACID TERT-BUTYL ESTER can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthese
At 0 ??, to 5-bromopyrazine-2-amine (5736.8mg, 32.97mmol) in CH2Cl2 (80mL) solution was added 4-DMAP (403.2mg, 3.30mmol); then at 0 ?? drop two A solution of di-tert-butyl carbonate (11.4ml, 3.30mmol) in CH2Cl2; the mixture was stirred at room temperature; after the completion of the reaction was monitored by TLC, the solution was washed with brine, dried over Na2SO4, filtered, and concentrated in vacuo; the crude product was chromatographed on a silica gel column Method, purified with ethyl acetate/petroleum ether (1/2) to obtain a white solid product (7250.4 mg, yield 80.2%).
(5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 77)Lieferanten
- (5-BROMOPYRAZIN-2-YL)CARBAMIC ACID TERT-BUTYL ESTER
- (5-BROMOPYRAZINYL)CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER
- tert-Butyl (5-bromopyrazin-2-yl)
- N-Boc-2-Amino-5-bromopyrazine
- 2-Amino-5-bromopyrazine, 2-BOC
- CarbaMicacid,(5-broMopyrazinyl)-,1,1-diMethylethylester
- 2-Amino-5-bromopyrazine, 2-BOC protected
- tert-Butyl (5-bromopyrazin-2-yl)carbamate, 2-Bromo-5-[(tert-butoxycarbonyl)amino]-1,4-diazine
- 2-Bromo-5-(boc-amino)pyrazine
- 2-Amino-5-bromopyrazine, 2-BOC protected 98%
- Carbamic acid, N-(5-bromo-2-pyrazinyl)-, 1,1-dimethylethyl ester
- 2-(Boc-amino)-5-bromopyrazine
- 914349-79-4
