ANTI-BIP Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-GRP78/BiP (GL-19) antibody produced in rabbit has been used in:

• western blotting
• immunocytochemistry
• immunohistochemistry

Allgemeine Beschreibung

GRP78/BiP is a Ca²⁺-binding molecular chaperone located in the endoplasmic reticulum (ER). It is a highly conserved protein.

Biochem/physiol Actions

GRP78 (78-kDa glucose-regulated protein) is essential for cell viability. GRP78/BiP is induced by stress-inducing agents or by conditions that adversely affect endoplasmic reticulum(ER) function, including oxidative stress, chemical toxicity, Ca2+ ionophores, inhibition of the ER Ca2+ -ATPase, inhibitors of glycosylation and hypoxia. GRP78/BiP is critical for maintenance of Ca2+ homeostasis and the prevention of apoptosis. GRP78/BiP levels are reduced in Alzheimer′s disease brains and the decreased expression of GRP78/BiP is found associated with mis-sense mutations in presenilin-1 (PS-1).

ANTI-BIP Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-BIP Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Shanghai Huzhen Industrial Co., LTD	021-60345367 13916550749	sales@shzbio.com	China	9966	58

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• ANTI-IMMUNOGLOBULIN HEAVY CHAIN BINDING PROTEIN
• ANTI-GRP78/BIP (ET-21)
• ANTI-GRP78/BIP (GL-19)
• ANTI-GRP78, RAT
• ANTI-GRP78, RAT (RABBIT)
• ANTI-GRP78
• ANTI-GRP78 (645-354) RABBIT PAB
• ANTI-GLUCOSE REGULATED PROTEIN 78
• ANTI-78-KDA GLUCOSE-REGULATED PROTEIN
• ANTI-78-KDA GLUCOSE-REGULATING PROTEIN
• ANTI-BIP
• ANTI-BIP (645-354) RABBIT PAB
• ANTI-BIP, RAT
• Anti-LEM domain containing 3
• Anti-LEMD3 antibody produced in rabbit
• Anti-MAN1
• Anti-GRP78/BiP (ET-21) antibody produced in rabbit
• Anti-BMP-3b
• Anti-Bone Morphogenetic Protein 3b precursor
• Anti-Bone-inducing protein
• Anti-GDF-10
• Anti-GDF10 antibody produced in rabbit
• Anti-Growth/differentiation factor 10
• Anti-Integral inner nuclear membrane protein
• Monoclonal Anti-LEMD3 antibody produced in mouse
• Anti-LEMD3 (426-440) antibody produced in rabbit
• Anti-LEMD3 Inner nuclear membrane protein Man1
• Anti-LEMD3 (701-715) antibody produced in rabbit
• BMP3B
• BMP-3b
• GDF10
• Anti-GRP78/BiP (GL-19) antibody produced in rabbit
• Anti-Heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
• Anti-HSPA5 antibody produced in rabbit