LAPAQUISTAT
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LAPAQUISTAT Eigenschaften
- Schmelzpunkt:
- 194-196℃
- Siedepunkt:
- 826.4±65.0 °C(Predicted)
- Dichte
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- L?slichkeit
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 4.66±0.10(Predicted)
- Farbe
- White
Sicherheit
LAPAQUISTAT Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
A novel squalene synthase inhibitor. Lapaquistat acetate decreased plasma cholesterol and triglyceride levels, by lowering lipoproteins containing apoB100. Treatment with Lapaquistat acetate increased collagen concentration and transformed coronary plaques into fibromuscular plaques. Lapaquistat acetate also suppressed the expression of matrix metalloproteinase-1 and plasminogen activator inhibitor-1 in the plaque and increased peripheral coenzyme Q10 levels.Antiarteriosclerotics.LAPAQUISTAT Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
LAPAQUISTAT Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 29)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6312 | 58 |
Alfa Chemistry | |
Info@alfa-chemistry.com | United States | 24072 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
ZHIWE CHEMTECH CO LTD | 021-20221225 13917446399 |
sales@zhiwe.net | China | 628 | 61 |
LGM Pharma | 1-(800)-881-8210 |
inquiries@lgmpharma.com | United States | 2123 | 70 |
Chemsky (shanghai) International Co.,Ltd | 021-50135380 |
shchemsky@sina.com | China | 15402 | 60 |
Wulechem Co., Ltd. | 13761914825 |
wulesian@wulechem.com | China | 297 | 58 |
SPIRO PHARMA | |
eric_feng1954@126.com | China | 9248 | 55 |
Nanjing NingFan Pharm-Tech CO. LTD. | 17368696818 |
China | 1984 | 58 |
- LAPAQUISTAT
- Lapaquistat and Lapaquistat Acetate
- Lapaquistat Acetate
- 2-[1-[2-[1-(3-Acetoxy-2,2-diMethylpropyl)-7-chloro-5(S)-(2,3-diMethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3(R)-yl]acetyl]piperidin-4-yl]acetic acid
- TAK-475
- 1-[[(3R,5S)-1-[3-(Acetyloxy)-2,2-dimethylpropyl]-7-chloro-5-(2,3-dimethoxyphenyl)-1,2,3,5-tetrahydro-2-oxo-4,1-benzoxazepin-3-yl]acetyl]-4-piperidineacetic acid
- CS-1400
- Lapaquistat Acetate (TAK-475)
- 4-Piperidineacetic acid, 1-[2-[(3R,5S)-1-[3-(acetyloxy)-2,2-dimethylpropyl]-7-chloro-5-(2,3-dimethoxyphenyl)-1,2,3,5-tetrahydro-2-oxo-4,1-benzoxazepin-3-yl]acetyl]-
- 2-(1-(2-((3R,5S)-1-(3-Acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid
- 189060-13-7
- C33H41ClN2O9
- Amines
- Chiral Reagents
- Heterocycles
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals