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CYCLO(-PRO-VAL)

CYCLO(-PRO-VAL) Struktur
2854-40-2
CAS-Nr.
2854-40-2
Englisch Name:
CYCLO(-PRO-VAL)
Synonyma:
Cyclo(Val-Pro);CYCLO(-PRO-VAL);Cyclo(L-Val-L-Pro-);Cyclo(L-Pro-L-Val-);2854-40-2/5654-87-5;Cyclo(L-prolyl-L-valyl);CYCLO(L-PROLYL-L-VALINE);Cyclo(L-Pro-L-Val),CYCLO(-PRO-VAL);(3S,8aS)-3-Isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione;(3S,8aα)-3β-Isopropyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione
CBNumber:
CB0132749
Summenformel:
C10H16N2O2
Molgewicht:
196.25
MOL-Datei:
2854-40-2.mol

CYCLO(-PRO-VAL) Eigenschaften

Schmelzpunkt:
190-192 °C
Siedepunkt:
420.7±34.0 °C(Predicted)
Dichte
1.17±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
Chloroform (Slightly, Sonicated), Methanol (Slightly)
Aggregatzustand
Solid
pka
13.15±0.40(Predicted)
Farbe
White to Off-White
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

CYCLO(-PRO-VAL) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Cyclo(L-Pro-L-Val) is a diketopiperazine that has been found in the marine sponge T. ignis, the bacterium B. pumilus, and the fungus A. fumigatus, among others. It is active against the bacteria S. aureus and B. subtilis (MICs = 16.3 and 18.2 μg/ml, respectively) but not E. coli (MIC = >20 μg/ml). Cyclo(L-Pro-L-Val) inhibits activation of a LuxR-dependent E. coli biosensor by the quorum-sensing molecule 3-oxo-hexanoyl-homoserine lactone (IC50 = 0.4 mM) and activates violacein pigment production in the LuxR-dependent C. violaceum acyl homoserine lactone reporter strain CV026. However, it does not activate or inhibit lacZ-based reporter fusions in S. liquefaciens or A. tumefaciens.

Verwenden

Cyclo(L-Pro-L-Val) is a diketopiperazine formed by the fusion of valine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Pro-L-Val) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Pro-L-Val) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of the cyclo(L-Pro-L-Val) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.

CYCLO(-PRO-VAL) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

9-(2'-ACETOXYETHOXYMETHYL)-GUANINE

CYCLO(-PRO-VAL) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 76)Lieferanten
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TargetMol Chemicals Inc.
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2854-40-2()Verwandte Suche:

  • CYCLO(-PRO-VAL)
  • (3S,8aS)-3-Isopropyl-6,7,8,8aα-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione
  • (3S,8aS)-3β-Isopropyl-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione
  • (3S,8aS)-Octahydro-3-(1-methylethyl)pyrrolo[1,2-a]pyrazine-1,4-dione
  • (3S,8aα)-3β-Isopropyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • Cyclo(L-Pro-L-Val-)
  • Cyclo(L-Val-L-Pro-)
  • Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-, (3S,8aS)-
  • (3S,8aS)-3-propan-2-yl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • Cyclo(L-prolyl-L-valyl)
  • CYCLO(L-PROLYL-L-VALINE)
  • (3S,8aS)-3-(propan-2-yl)-octahydropyrrolo[1,2-a]p yrazine-1,4-dione
  • (3S,8aS)-3-Isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • Cyclo(L-Pro-L-Val),CYCLO(-PRO-VAL)
  • 2854-40-2/5654-87-5
  • Cyclo(Val-Pro)
  • 2854-40-2
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