鹽酸呋喃硫胺
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- CAS號:
- 2105-43-3
- 英文名:
- FURSULTIMINE HYDROCHLORIDE
- 英文別名:
- TTFD hydrochloride;FURSULTIMINE HYDROCHLORIDE;FURSULTIMINE HYDROCHLORIDE USP/EP/BP;Fursultiamine Hydrochloride
（mixture of isomers）;Thiamin tetrahydrofurfuryl disulfide hydrochloride;Thiamine tetrahydrofurfuryl disulfide hydrochloride;N-(4-Amino-2-methylpyrimidin-5-ylmethyl)-N-{4-hydroxy-1-methyl-2-[(RS)-tetrahydrofuran-2-ylmethyldisulfanyl]but-1-en-1-y;N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]but-1-en-1-yl]formamide monohydrochloride;Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-, monohydrochloride (8CI);Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-, monohydrochloride
- 中文名:
- 鹽酸呋喃硫胺
- 中文別名:
- 鹽酸呋喃舒敏;鹽酸呋喃磺胺;鹽酸呋喃硫胺;呋喃硫胺及鹽酸呋喃硫胺;N-[(4-氨基-2-甲基-5-嘧啶基)甲基]-N- [4-羥基-1-甲基-2-[[(四氫-2-呋喃基)甲基]二硫]-1-丁烯-1-基]-甲酰胺鹽酸鹽
- CBNumber:
- CB8419073
- 分子式:
- C17H27ClN4O3S2
- 分子量:
- 435
- MOL File:
- 2105-43-3.mol
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鹽酸呋喃硫胺化學性質(zhì)
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熔點:
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160 °C (decomp)
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溶解度:
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DMSO (Slightly, Heated), Methanol (Slightly)
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形態(tài):
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Solid
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顏色:
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White to Off-White
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鹽酸呋喃硫胺性質(zhì)、用途與生產(chǎn)工藝
鹽酸呋喃硫胺為白色或微黃色結(jié)晶性粉末，無臭或略有類似蒜臭。在水中或丙酮中微溶；在甲醇、乙醇或氯仿中易溶；在苯或乙醚中幾乎不溶。熔點130-136℃ (分解)。
鹽酸呋喃硫胺適用于維生素B1的腳氣病或Wernicke腦病的治療，亦可用于維生素B1缺乏引起的周圍神經(jīng)炎、消化不良等的輔助治療。
鹽酸呋喃硫胺是維生素 B1的新型衍生物，在體內(nèi)迅速轉(zhuǎn)化為活性硫胺，不為體內(nèi)硫胺酶分解，對組織親和力強，臟器濃度高，血中濃度高，維持時間長，具有高效、長效、低毒的特性。
鹽酸呋喃硫胺偶見頭昏、乏力、惡心、嘔吐，停藥后即消失；注射局部偶有硬包塊，熱敷或停藥后可漸消失。
鹽酸呋喃硫胺
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
2105-43-3, 鹽酸呋喃硫胺 相關(guān)搜索:
- 有機中間體
- C17H27ClN4O3S2
- C17H26N4O3S2HCl
- 鹽酸呋喃舒敏
- 鹽酸呋喃磺胺
- N-[(4-氨基-2-甲基-5-嘧啶基)甲基]-N- [4-羥基-1-甲基-2-[[(四氫-2-呋喃基)甲基]二硫]-1-丁烯-1-基]-甲酰胺鹽酸鹽
- 鹽酸呋喃硫胺
- 呋喃硫胺及鹽酸呋喃硫胺
- 2105-43-3
- FURSULTIMINE HYDROCHLORIDE USP/EP/BP
- Fursultiamine Hydrochloride
（mixture of isomers）
- TTFD hydrochloride
- Thiamin tetrahydrofurfuryl disulfide hydrochloride
- Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-, monohydrochloride
- Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-, monohydrochloride (8CI)
- Thiamine tetrahydrofurfuryl disulfide hydrochloride
- N-(4-Amino-2-methylpyrimidin-5-ylmethyl)-N-{4-hydroxy-1-methyl-2-[(RS)-tetrahydrofuran-2-ylmethyldisulfanyl]but-1-en-1-y
- N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]but-1-en-1-yl]formamide monohydrochloride
- FURSULTIMINE HYDROCHLORIDE