UNC-2371A
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- CAS號(hào):
- 1429882-07-4
- 英文名:
- UNC-2371A
- 英文別名:
- UNC2371;MRX-2843;UNC-2371A;UNC2371;MRX-2843;MRX-2843 (UNC2371);MRX-2843, 10 mM in DMSO;MRX-2843?(Synonyms: UNC2371;trans-4-(2-((2-Cyclopropylethyl)amino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol;(1r,4r)-4-(2-(2-cyclopropylethylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol;Cyclohexanol, 4-[2-[(2-cyclopropylethyl)amino]-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-, trans-
- 中文名:
- UNC-2371A
- 中文別名:
- FLT3抑制劑;化合物MRX-2843;MERTK和FLT3抑制劑(MRX-2843);化合物MRX-2843,10 MM DMSO 溶液;反式-4-[2-[(2-環(huán)丙基)氨基]-5-[4-[(4-甲基-1-哌嗪基)甲基]苯基]-7H-吡咯并[2,3-D]嘧啶-7-基]環(huán)己醇;反式-4-(2-((2-環(huán)丙基乙基)氨基)-5-(4-((4-甲基哌嗪-1-基)甲基)苯基)-7H-吡咯并[2,3-D]嘧啶-7-基)環(huán)己醇;(1R,4R)-4-{2-[(2-環(huán)丙基乙基)氨基]-5-{4-[(4-甲基哌嗪-1-取代)甲基]苯基}吡咯[2,3-D]嘧啶-7-取代}環(huán)己基-1-醇
- CBNumber:
- CB73168663
- 分子式:
- C29H40N6O
- 分子量:
- 488.67
- MOL File:
- 1429882-07-4.mol
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UNC-2371A化學(xué)性質(zhì)
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熔點(diǎn):
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>137°C (dec.)
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沸點(diǎn):
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697.3±65.0 °C(Predicted)
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密度:
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1.31±0.1 g/cm3(Predicted)
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儲(chǔ)存條件:
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Refrigerator
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溶解度:
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Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
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酸度系數(shù)(pKa):
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14.63±0.40(Predicted)
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形態(tài):
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Solid
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顏色:
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White to Pale Beige
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UNC-2371A性質(zhì)、用途與生產(chǎn)工藝
MRX-2843 (UNC2371) 是酪氨酸激酶 MERTK 和 FLT3 的口服活性雙重抑制劑，對(duì)應(yīng)的IC50值分別為1.3 nM和0.64 nM。
| Target | Value |
FLT3
(Cell-free assay)
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0.64 nM
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MERTK
(Cell-free assay)
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1.3 nM
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UNC-2371A
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS編號(hào) | 包裝 | 價(jià)格 |
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| 2025/02/08 | HY-101549 | 1429882-07-4
MRX-2843 | 1429882-07-4 | 5mg | 1800元 |
| 2025/02/08 | HY-101549 | 1429882-07-4
MRX-2843 | 1429882-07-4 | 10mM * 1mLin DMSO | 1935元 |
1429882-07-4, UNC-2371A 相關(guān)搜索:
- 化學(xué)試劑
- 高純?cè)噭?/font>
- 抑制劑
- 標(biāo)準(zhǔn)品
- 細(xì)胞生物學(xué)試劑
- C29H40N6O
- 化合物MRX-2843,10 MM DMSO 溶液
- 反式-4-(2-((2-環(huán)丙基乙基)氨基)-5-(4-((4-甲基哌嗪-1-基)甲基)苯基)-7H-吡咯并[2,3-D]嘧啶-7-基)環(huán)己醇
- 反式-4-[2-[(2-環(huán)丙基)氨基]-5-[4-[(4-甲基-1-哌嗪基)甲基]苯基]-7H-吡咯并[2,3-D]嘧啶-7-基]環(huán)己醇
- (1R,4R)-4-{2-[(2-環(huán)丙基乙基)氨基]-5-{4-[(4-甲基哌嗪-1-取代)甲基]苯基}吡咯[2,3-D]嘧啶-7-取代}環(huán)己基-1-醇
- FLT3抑制劑
- 化合物MRX-2843
- MERTK和FLT3抑制劑(MRX-2843)
- 1429882-07-4
- MRX-2843, 10 mM in DMSO
- trans-4-(2-((2-Cyclopropylethyl)amino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol
- UNC 2371,FLT3,Fms like tyrosine kinase 3,CD135,inhibit,MRX2843,Cluster of differentiation antigen 135,UNC-2371,Inhibitor,MRX-2843,MRX 2843
- MRX-2843?(Synonyms: UNC2371
- Cyclohexanol, 4-[2-[(2-cyclopropylethyl)amino]-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-, trans-
- UNC2371;MRX-2843
- UNC2371
- MRX-2843
- MRX-2843 (UNC2371)
- (1r,4r)-4-(2-(2-cyclopropylethylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol
- UNC-2371A