4,4’,4"-三氨基三苯甲烷是丙型肝炎病毒解旋酶的抑制劑。4,4’,4"-三氨基三苯甲烷具有致癌活性,增加了動(dòng)物直腸內(nèi)皮系統(tǒng)腫瘤的發(fā)生率。
HCV helicase
Tris(4-aminophenyl)methane (Compound 8) shows weak HCV helicase inhibition (30% inhibition at 100 μM). To preserve RNA in a biological sample for analysis, the sample is incubated with an RNA preservative capable of precipitating RNA in an aqueous solution, such as a triphenylmethane dye (e.g., methyl green, crystal violet, pararosaniline, or Tris(4-aminophenyl)methane), cresyl violet, or cobalt ions. RNA preservation may be used in an immunostaining assay and other histochemical methods.