99011-78-6
中文名稱
鹽酸咪喹莫特
英文名稱
IMiquiMod (hydrochloride)
CAS
99011-78-6
分子式
C14H17ClN4
分子量
276.765
MOL 文件
99011-78-6.mol
99011-78-6 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
熔點(diǎn)>300 °C
儲(chǔ)存條件Keep in dark place,Sealed in dry,Room Temperature
溶解度≥3.59 mg/mL in EtOH with ultrasonic; ≥5.54 mg/mL in DMSO with gentle warming and ultrasonic; ≥7.34 mg/mL in H2O with ultrasonic
形態(tài)固體
顏色White to off-white
鹽酸咪喹莫特價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-B0180A | 鹽酸咪喹莫特 Imiquimod hydrochloride | 99011-78-6 | 100mg | 485元 |
| 2024/11/08 | HY-B0180A | 鹽酸咪喹莫特 Imiquimod hydrochloride | 99011-78-6 | 10mM * 1mLin DMSO | 660元 |
| 2024/11/08 | HY-B0180A | 鹽酸咪喹莫特 Imiquimod hydrochloride | 99011-78-6 | 200mg | 710元 |
常見(jiàn)問(wèn)題列表
生物活性
Imiquimod hydrochloride (R 837 hydrochloride) 是一種選擇性的 toll 樣受體 7 (TLR7) 激動(dòng)劑，作為一種免疫反應(yīng)調(diào)節(jié)劑。Imiquimod hydrochloride 在體內(nèi)表現(xiàn)出抗病毒和抗腫瘤作用。Imiquimod hydrochloride 可用于外生殖器、肛周疣、癌癥和 COVID-19 的研究。靶點(diǎn)
|
TLR7
|
HSV-1
|
體內(nèi)研究
In animal models, Imiquimod hydrochloride stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod hydrochloride stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α.