| Identification | Back Directory | [Name]
IMiquiMod (hydrochloride) | [CAS]
99011-78-6 | [Synonyms]
IMiquiMod (hydrochloride)
Imiquimod hydrochloride (R 837 hydrochloride) | [Molecular Formula]
C14H17ClN4 | [MDL Number]
MFCD28168057 | [MOL File]
99011-78-6.mol | [Molecular Weight]
276.765 |
| Chemical Properties | Back Directory | [Melting point ]
>300 °C | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
≥3.59 mg/mL in EtOH with ultrasonic; ≥5.54 mg/mL in DMSO with gentle warming and ultrasonic; ≥7.34 mg/mL in H2O with ultrasonic | [form ]
solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
imiquimod hydrochloride is an immune response modifier that acts as a toll-like receptor 7 agonist and is commonly used topically to treat warts on the skin of the genital and anal areas. | [in vivo]
In animal models, Imiquimod hydrochloride stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod hydrochloride stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumor necrosis factor (TNF)-α.
| [target]
|
|
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://m.is0513.com/ShowSupplierProductsList927327/0.htm |
|