916888-47-6
916888-47-6 結構式
基本信息
英文別名
Resolvin D35,7,9,13,15,19-Docosahexaenoic acid, 4,11,17-trihydroxy-, (4S,5Z,7E,9E,11R,13Z,15E,17S,19Z)-
物理化學性質
儲存條件-20°C儲存
溶解度DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.4): 0.05 mg/ml
形態(tài)Liquid
顏色Colorless to light yellow
Resolvin D3價格(試劑級)
| 報價日期 | 產品編號 | 產品名稱 | CAS號 | 包裝 | 價格 |
| 2025/02/08 | HY-136540 | Resolvin D3 Resolvin D3 | 916888-47-6 | 25μg(265.6μM * 250μL in Ethanol) | 8800元 |
常見問題列表
生物活性
Resolvin D3 (RvD3) 是二十二碳六烯酸 (DHA) 衍生的介體。Resolvin D3 在關節(jié)炎中失調，可減輕關節(jié)炎癥。體外研究
RvD3 (RvD3; 10 nM) significantly inhibits tumor necrosis factor-α–induced NF-κB activation in A549 epithelial cells.
體內研究
Resolvin D3 (RvD3; 100 ng/100 μl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis.
| Animal Model: | Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice |
| Dosage: | 100 ng/100 μl |
| Administration: | IP; daily for 6 days |
| Result: | Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis. |