| Identification | Back Directory | [Name]
Resolvin D3 | [CAS]
916888-47-6 | [Synonyms]
Resolvin D3
5,7,9,13,15,19-Docosahexaenoic acid, 4,11,17-trihydroxy-, (4S,5Z,7E,9E,11R,13Z,15E,17S,19Z)- | [Molecular Formula]
C22H32O5 | [MDL Number]
MFCD34470542 | [MOL File]
916888-47-6.mol | [Molecular Weight]
376.49 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.4): 0.05 mg/ml | [form ]
Liquid | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
Resolvin D3 acts as a n anti-inflammatory and anti-arthritic agent. | [Definition]
ChEBI: Resolvin D3 is a member of the class of resolvins that is (5Z,7E,9E,13Z,15E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 4, 11 and 17 (the 4S,11R,17S-stereoisomer). It has a role as an anti-inflammatory agent and a human xenobiotic metabolite. It is a resolvin, a secondary allylic alcohol, a triol and a hydroxy polyunsaturated fatty acid. | [in vivo]
Resolvin D3 (RvD3; 100 ng/100 μl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis[1]. | Animal Model: | Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice[1] | | Dosage: | 100 ng/100 μl | | Administration: | IP; daily for 6 days | | Result: | Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis.
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