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646-01-5

中文名稱 3-甲基硫代丙酸
英文名稱 3-METHYLTHIOPROPIONIC ACID
CAS 646-01-5
分子式 C4H8O2S
分子量 120.17
MOL 文件 646-01-5.mol
更新日期 2024/08/05 10:20:49
646-01-5 結(jié)構(gòu)式 646-01-5 結(jié)構(gòu)式

基本信息

中文別名
3-甲基硫代丙酸
3-(甲硫基)丙酸
3-(甲基硫代)丙酸,97%
英文別名
RARECHEM AL BE 0161
4-Thiapentanoic acid
3-METHYLTHIO PROPIONATE
3-METHYTHIOPROPIONIC ACID
3-METHYLTHIOPROPIONIC ACID
3-(METHYLTHIO)PROPANOIC ACID
3-(methy1thio)propionic acid
3-(Metghylthio)propionic acid
3-METHYLMERCAPTOPROPIONIC ACID
3-(Methylthio)propionicAcid>
所屬類別
有機(jī)原料:有機(jī)硫化合物

物理化學(xué)性質(zhì)

熔點(diǎn)16°C
沸點(diǎn)130°C 2mm
密度1.160
折射率1.4884
閃點(diǎn)130°C/15mm
儲存條件-20°C儲存
酸度系數(shù)(pKa)4.29±0.10(Predicted)
形態(tài)粉末至塊狀至透明液體
顏色白色或無色至淺黃色
氣味 (Odor)sweet sulfurous
水溶解性Water : 25 mg/mL (208.04 mM)
BRN1743054
LogP0.458 (est)

安全數(shù)據(jù)

危險(xiǎn)性符號(GHS)GHS hazard pictograms
GHS05
警示詞危險(xiǎn)
危險(xiǎn)性描述H314-H318
危險(xiǎn)類別碼34
安全說明26-36/37/39
危險(xiǎn)品運(yùn)輸編號3265
危險(xiǎn)等級8
包裝類別II
海關(guān)編碼29309090
3-甲基硫代丙酸價(jià)格(試劑級)
報(bào)價(jià)日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價(jià)格
2024/08/19L128613-(甲基硫代)丙酸, 98%
3-(Methylthio)propionic acid, 98%
646-01-510g304元
2024/08/19L128613-(甲基硫代)丙酸, 98%
3-(Methylthio)propionic acid, 98%
646-01-550g991元
2024/08/19M08113-甲硫基丙酸
3-(Methylthio)propionic Acid
646-01-525G250元

常見問題列表

生物活性
3-(Methylthio)propionic acid (3-methylthiopropionate, 4-Thiapentanoic acid, 3-Methylsulfanylpropionic acid)是一種硫代脂肪酸,在體外,它是哺乳動物蛋氨酸代謝的中間產(chǎn)物。
靶點(diǎn)

Human Endogenous Metabolite

體外研究

Methionine has consistently been shown to be the most toxic amino acid in experiments devised to assess the relative toxicity of dietary amino acids. 3-methylthiopropionate is an intermediate in methionine catabolism in rat and monkey liver in vitro . This pathway appears to account for a major portion of methionine oxidation in vitro . Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts directly related to the concentration of methionine in the medium. The first intermediate in the pathway may be the keto acid, which is then oxidatively decarboxylated to 3-methylthiopropionic acid. The purified 3-MTPA has antifungal activity in assays using F. oxysporum as a model fungus. Daily measurements of shoot and root length shows severe inhibition of seed germination and root and shoot development at concentrations above 12mg for partially purified extracts. 3-methylthiopropionic acid ethyl ester possesses potential anticarcinogenic properties by inducing differentiation in well-differentiated colon cancer cells. Treatment of RCM-1 cells for 4 days with 3-methylthiopropionic acid ethyl ester between the doses of 0.25 and 2 mM progressively increases the percent area occupied by duct structures relative to the control, and also induces an increase in the number and the maximum diameter of the ducts in each culture plate.

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