55-43-6
中文名稱
N-(2-氯乙基)二芐胺鹽酸鹽
英文名稱
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
CAS
55-43-6
EINECS 編號
200-234-5
分子式
C16H19Cl2N
MDL 編號
MFCD00012518
分子量
296.23
MOL 文件
55-43-6.mol
更新日期
2025/02/08 08:31:03
55-43-6 結構式
基本信息
中文別名
N-(2-氯乙基)二芐胺鹽酸鹽二芐氨基氯乙烷鹽酸鹽
鹽酸二芐乃明
N,N-聯(lián)芐基-2-氯乙胺鹽酸鹽
英文別名
DIBENAMINE HYDROCHLORIDEN-(2-CHLOROETHYL)DIBENZYLAMINE HCL
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
N,N'-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE
N,N-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE
N,N-DIBENZYLAMINOETHYLCHLORIDE HYDROCHLORIDE
N,N-DIBENZYL-BETA-CHLOROETHYLAMINE HYDROCHLORIDE
dibenzylchlorethylaminehydrochloride
n-(2-chloroethyl)-dibenzylaminhydrochloride
n-(2-chloroethyl)-n-(phenylmethyl)-benzenemethanaminhydrochloride
dibenzyl(2-chloroethyl)ammonium chloride
n,n-dibenzyl-2-chloroethylamineHCl
DIBENZYLAMINE,N-(2-CHLOROETHYL)-,HYDROCHLORIDE
N-(2-Chloroethyl)-N-(phenylmethyl)benzmetanamine chlorohydrate
Sympatholytin hydrochloride
所屬類別
有機原料：無環(huán)單胺、多胺及其衍生物和鹽物理化學性質
熔點190-193 °C(lit.)
沸點449.72°C (rough estimate)
密度1.1507 (rough estimate)
折射率1.6300 (estimate)
儲存條件Inert atmosphere,Room Temperature
溶解度在甲醇中幾乎透明
形態(tài)結晶粉末
顏色白色至灰白色
Merck2138
CAS 數(shù)據(jù)庫55-43-6(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞警告
危險性描述H315-H319-H335
危險品標志Xi
危險類別碼R36/37/38
安全說明S26-S37/39
WGK Germany3
RTECS號HQ6825000
危險等級IRRITANT
海關編碼29214900
毒性LD50 s.c. in mice: 800 mg/kg (Nickerson, Nomaguchi)
N-(2-氯乙基)二芐胺鹽酸鹽價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/02/08 | HY-128380 | N-(2-氯乙基)二芐胺鹽酸鹽 Dibenamine hydrochloride | 55-43-6 | 1 g | 240元 |
| 2025/02/08 | HY-128380 | N-(2-氯乙基)二芐胺鹽酸鹽 Dibenamine hydrochloride | 55-43-6 | 10mM * 1mLin DMSO | 264元 |
| 2025/02/08 | HY-128380 | N-(2-氯乙基)二芐胺鹽酸鹽 Dibenamine hydrochloride | 55-43-6 | 5 g | 760元 |
常見問題列表
生物活性
Dibenamine hydrochloride 是一種競爭和不可逆的腎上腺素能 (b>adrenergic) 阻斷劑，可以修飾腎上腺素的藥理作用。Dibenamine hydrochloride 對小鼠體內(nèi)腎上腺素的破壞率顯著增加。靶點
IC50: Adrenergic receptor
體外研究
Dibenamine (100 nM-10 μM) attenuates the degree of cocaine-induced increase in sensitivity to acetylcholine without any effect on acetylcholine-contraction in isolated vas deferens of guinea pig. Additionally, the degree of dibenamine-induced inhibition dependent on the concentration of dibenamine and inversely related to the concentration of cocaine.
體內(nèi)研究
Dibenamine hydrochloride (subcutaneous?injection; 25 mg/kg; 48 and 24 hr before the administration of CCl4) decreases the CHCl3, levels at 2 and 6 hr by 30-50 percent, but did not appreciably affect the half-life of CHCl3, in the liver.Pretreatment with Dibenamine apparently slows the conversion of Ccl4 to CHCL3.