5369-03-9
中文名稱
QX-314;QX314;N-ETHYLLIDOCAINE CHLORIDE
英文名稱
QX 314 chloride
CAS
5369-03-9
分子式
C16H27ClN2O
分子量
298.85
MOL 文件
5369-03-9.mol
5369-03-9 結(jié)構(gòu)式
基本信息
中文別名
化合物QX-314 CHLORIDE 英文別名
QX314.ClQX 314 CHLORIDE
N-Ethyllidocaine chloride
Lidocaine N-ethyl chloride
QX-314
QX314
N-ETHYLLIDOCAINE CHLORIDE
[2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium chloride
N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM CHLORIDE
[2-(2,6-dimethylanilino)-2-keto-ethyl]-triethyl-ammonium chloride
[2-[(2,6-dimethylphenyl)amino]-2-oxo-ethyl]-triethyl-azanium chloride
2-(2,6-Dimethylphenylamino)-N,N,N-triethyl-2-oxoethanaminium chloride
所屬類別
原料藥：鈣通道阻滯劑物理化學(xué)性質(zhì)
熔點(diǎn)209-211 °C
儲存條件Room temp
儲存條件Room temp
溶解度insoluble in EtOH; ≥14.95 mg/mL in DMSO with gentle warming; ≥22.3 mg/mL in H2O
形態(tài)固體
顏色白色
水溶解性Soluble in water (100mM)
QX-314價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | HY-108505 | QX-314 QX-314 chloride | 5369-03-9 | 5mg | 196元 |
| 2024/11/08 | HY-108505 | QX-314 QX-314 chloride | 5369-03-9 | 10mg | 315元 |
| 2024/11/08 | HY-108505 | QX-314 QX-314 chloride | 5369-03-9 | 25 mg | 600元 |
常見問題列表
生物活性
QX-314 chloride 是一種膜不滲透的鈉離子通道永久性電荷阻滯劑。靶點(diǎn)
sodium channel
體外研究
QX-314 chloride exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels (TRPV1) in vitro.
QX-314 chloride (1–60 mM) directly activates TRPV1 in a concentration-dependent manner.
QX-314 chloride (10 mM) inhibits calcium currents in hippocampal CA1 pyramidal neurons intracellular, and the low-threshold (T-type) Ca
2+
currents are on average < 45% of control amplitude.