41372-08-1
中文名稱
L-甲基多巴
英文名稱
alpha-Methyldopa sesquihydrate
CAS
41372-08-1
EINECS 編號
209-089-2
分子式
C10H15NO5
MDL 編號
MFCD00149280
分子量
229.23
MOL 文件
41372-08-1.mol
更新日期
2025/01/26 19:18:37
41372-08-1 結(jié)構(gòu)式
基本信息
中文別名
3-羥基-beta-甲基-L-酪氨酸水合物L-甲基多巴
2-甲基-3-(3,4-二羥基苯基)-L-丙氨酸
3-(3,4-二羥基苯基)-2-甲基-L-丙氨酸
3-羥基-Α-甲基-L-酪氨酸
(-)-甲基多巴
英文別名
(-)-3-(3,4-DIHYDROXYPHENYL)-2-METHYL-L-ALANINE SESQUIHYDRATE3-(3,4-DIHYDROXYPHENYL)-2-METHYL-L-ALANINE SESQUIHYDRATE
3-HYDROXY-ALPHA-METHYL-L-TYROSINE SESQUIHYDRATE
3-hydroxy-b-methyl-l-tyrosine hydrate
ALPHA-METHYL-DOPA SESQUIHYDRATE
(-)-ALPHA-METHYL-L-DOPA SESQUIHYDRATE
ALPHA-METHYL-L-DOPA SESQUIHYDRATE
methyl dopa sesquihydrate
(S)-2-AMINO-3-(3,4-DIHYDROXYPHENYL)-2-METHYLPROPIONIC ACID SESQUIHYDRATE
3-hydroxy-alpha-methyl-l-tyrosinhydrate(2:3)
hyperpax
L-METHYL DOPA USP24
L-Methyldopa sesquihydrate
3-(3,4-DIHYDROXYPHENYL)-2-METHYL-
MethyldopaUsp25
(-)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alaninesesquihydrate,99%
-METHYL-L-DOPA SESQUIHYDRATE
L-Tyrosine, 3-hydroxy-.alpha.-methyl-, hydrate (2:3)
à-methyl-l-dopa
L-(-)-ALPHA-METHYLDOPA ((-)-3-(3,4-DIHYDROXYPHENYL)-2-METHYL-L-ALANINE SESQUIHYDRATE)
所屬類別
原料藥：抗高血壓病藥物理化學(xué)性質(zhì)
熔點(diǎn)>300 °C(lit.)
儲存條件2-8°C
溶解度Slightly soluble in water, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute mineral acids.
形態(tài)neat
顏色白色至灰白色
旋光性 (optical activity)[α]25/D 13°, c = 1 in H2O
水溶解性0.1-1 g/100 mL at 23 ºC
敏感性Air & Light Sensitive
Merck13,6080
BRN2417244
穩(wěn)定性穩(wěn)定，但可能對光敏感。非常吸濕。在鎂、銅、鈷、鎳和鐵離子存在下進(jìn)行催化氧化。存放在干燥的環(huán)境中。
CAS 數(shù)據(jù)庫41372-08-1(CAS DataBase Reference)
L-甲基多巴價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | H56704 | (-)-3-(3,4-二羥基苯基)-2-甲基-L-丙氨酸 倍半水合物, 99% (-)-3,4-Dihydroxy-alpha-methyl-L-phenylalanine sesquihydrate, 99% | 41372-08-1 | 1g | 143元 |
| 2024/11/08 | H56704 | (-)-3-(3,4-二羥基苯基)-2-甲基-L-丙氨酸 倍半水合物, 99% (-)-3,4-Dihydroxy-alpha-methyl-L-phenylalanine sesquihydrate, 99% | 41372-08-1 | 5g | 680元 |
| 2020/09/30 | B22740 | (-)-甲基多巴, 99%
(-)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine sesquihydrate, 99% | 41372-08-1 | 1g | 132元 |
常見問題列表
生物活性
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate) 是一種 α-腎上腺素能激動劑 (對 α2-adrenergic receptors 有選擇性)。Methyldopa hydrate 是一種前藥，在中樞神經(jīng)系統(tǒng)中被代謝 (α-Methylepinephrine)。體內(nèi)研究
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment.
| Animal Model: | 60-day-old male rats |
| Dosage: | 200 mg/kg |
| Administration: | i.p. |
| Result: | Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration. |