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318290-98-1

中文名稱(chēng) 聯(lián)氟砜
英文名稱(chēng) Fluensulfone
CAS 318290-98-1
分子式 C7H5ClF3NO2S2
分子量 291.7
MOL 文件 318290-98-1.mol
更新日期 2025/03/05 08:26:54
318290-98-1 結(jié)構(gòu)式 318290-98-1 結(jié)構(gòu)式

基本信息

中文別名
氟砜靈
聯(lián)氟砜
氟噻蟲(chóng)砜
聯(lián)氟砜 標(biāo)準(zhǔn)品
聯(lián)氟砜、氟噻蟲(chóng)砜
氟砜靈, >98%
聯(lián)氟砜溶液, 100PPM
化合物FLUENSULFONE
FLUENSULFONE SOLUTION
5-氯-1,3-噻唑-2-基-3,4,4-三氟丁-3-烯-1-基砜
英文別名
MCW-2
Fluensulfone
Fluensulfone, >98%
Fluensulfone Solution
Fluensulfone Solution, 100ppm
5-chloro-2-(3,4,4-trifluorobut-3-enylsulfonyl)thiazole
5-Chloro-2-((3,4,4-trifluorobut-3-en-1-yl)sulfonyl)thiazole
5-Chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]thiazole
Thiazole, 5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]-
5-Chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]-1,3-thiazole
所屬類(lèi)別
生物化工:激動(dòng)劑抑制劑

物理化學(xué)性質(zhì)

熔點(diǎn)34 °C
沸點(diǎn)375.5±52.0 °C(Predicted)
密度1.577±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
酸度系數(shù)(pKa)-3.12±0.10(Predicted)
形態(tài)結(jié)晶固體
InChIInChI=1S/C7H5ClF3NO2S2/c8-5-3-12-7(15-5)16(13,14)2-1-4(9)6(10)11/h3H,1-2H2
InChIKeyXSNMWAPKHUGZGQ-UHFFFAOYSA-N
SMILESS1C(Cl)=CN=C1S(CC/C(/F)=C(/F)\F)(=O)=O
溶解度溶于乙醇、DMSO、二甲基甲酰胺等有機(jī)溶劑。
顏色黃色樹(shù)脂狀

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H302-H315-H319-H335
防范說(shuō)明P261-P305+P351+P338

常見(jiàn)問(wèn)題列表

殺蟲(chóng)劑

聯(lián)氟砜是化學(xué)防治植物寄生線蟲(chóng)的新型殺線蟲(chóng)劑, 可以防除蔬菜和水果上的根結(jié)線蟲(chóng)。

合成方法

聯(lián)氟砜可經(jīng)如下反應(yīng)制得:

聯(lián)氟砜合成

體外研究

Lower concentrations of Fluensulfone delay development: 100 μM Fluensulfone causes a slight delay as at 66 h fewer worms have reached the adult stage whilst at 300 μM no worms reach the adult stage at 66 h and some fail to reach L4. Adult hermaphrodites lay fewer eggs in the presence of 1 mM Fluensulfone. Fluensulfone is also found to reduce the viability of eggs. After 3 h incubation with 100 μM to 1 mM Fluensulfone the thrashing rate is significantly inhibited, with maximal inhibition occurring with 1 mM. After 1 h both 300 μM and 1 mM Fluensulfone cause a significant and reversible inhibition of pharyngeal pumping relative to the vehicle control. Fluensulfone (500 μM) inhibits the frequency of body bends in one day old adult hermaphrodites off food after 2 h exposure.

體內(nèi)研究

In an in vivo investigation, female mice are treated with Fluensulfone (or isoniazid as a positive control) for 3 and 7 days. Quantification of the cell proliferation by manual counting of BrdU-positive and BrdU-negative cells in the bronchiolar epithelium reveals an approximately fourfold increase of cell proliferation upon treatment with Fluensulfone and the positive control isoniazid compare with control. Increased cell proliferation is observed at 3 days but have reverted to the control level at day 7 .

聯(lián)氟砜 價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱(chēng)CAS號(hào)包裝價(jià)格
2025/02/08HY-107771聯(lián)氟砜
Fluensulfone
318290-98-11 mg223元
2025/02/08HY-107771聯(lián)氟砜
Fluensulfone
318290-98-12mg329元
2025/02/08HY-107771聯(lián)氟砜
Fluensulfone
318290-98-15mg516元
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