27750-13-6
中文名稱
藤黃內(nèi)酯
英文名稱
HYDROXYCITRIC ACID LACTONE, (-)-(P)
CAS
27750-13-6
分子式
C6H6O7
分子量
190.11
MOL 文件
27750-13-6.mol
27750-13-6 結構式
基本信息
中文別名
藤黃內(nèi)酯(-)-羥基檸檬酸內(nèi)酯
英文別名
Garcinia lactone(-)-Hydroxycitric acid lactone
HYDROXYCITRIC ACID LACTONE, (-)-(P)
3-C-Carboxy-2-deoxy-D-erythropentaric acid 1,4-lactone
D-erythro-Pentaric acid, 3-C-carboxy-2-deoxy-, 1,4-lactone
(2S,3S)-3-Hydroxy-5-oxotetrahydrofuran-2,3-dicarboxylic acid
所屬類別
分析化學：離子色譜試劑物理化學性質(zhì)
沸點673.6±55.0 °C(Predicted)
密度1.976
溶解度DMSO : 250 mg/mL (1315.03 mM; Need ultrasonic)
酸度系數(shù)(pKa)2.40±0.40(Predicted)
形態(tài)neat
顏色White to off-white
常見問題列表
生物活性
(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一種減肥藥，也是一種很受歡迎的減肥食品補充劑。(-)-Hydroxycitric acid lactone 是一種有效的 ATP-檸檬酸裂解酶 抑制劑。(-)-Hydroxycitric acid lactone 催化檸檬酸鹽線粒體外裂解為草酰乙酸和乙酰輔酶 A，限制了脂肪酸合成所需乙酰輔酶 A 單位的可用性。體內(nèi)研究
(-)-Hydroxycitric acid lactone (1000-3000mg/kg; fed for a period of 4 weeks) significantly decreases body weight at 2000 and 3000 mg/kg in chicken.
| Animal Model: | 1-day-old male broiler chickens |
| Dosage: | 1000, 2000, 3000 mg/kg |
| Administration: | Fed for a period of 4 weeks |
| Result: | Body weight and average daily gain (ADG) in the 2000 mg/kg and 3000 mg/kg were significantly lower. |