2601-90-3
中文名稱
N-OLEOYLGLYCINE
英文名稱
N-OLEOYLGLYCINE
CAS
2601-90-3
分子式
C20H37NO3
分子量
339.51
MOL 文件
2601-90-3.mol
更新日期
2024/11/12 15:51:36
2601-90-3 結(jié)構(gòu)式
基本信息
中文別名
2-油酰胺基乙酸化合物N-OLEOYL GLYCINE
2-[[(Z)-十八碳-9-烯?；鵠氨基]乙酸
英文別名
OleoylglycineN-OLEOYLGLYCINE
N-Oleoylglycine >=98%
N-(9Z-OCTADECENOYL)-GLYCINE
N-[(Z)-1-Oxo-9-octadecenyl]glycine
(Z)-N-(1-oxo-9-octadecenyl)glycine
N-(1-OXO-9-OCTADECENYL)-(Z)-GLYCINE
Glycine, N-[(9Z)-1-oxo-9-octadecen-1-yl]-
所屬類別
生物化工：甘氨酸類衍生物物理化學(xué)性質(zhì)
熔點(diǎn)77-78 °C
沸點(diǎn)525.6±43.0 °C(Predicted)
密度0.962±0.06 g/cm3(Predicted)
儲(chǔ)存條件−20°C
溶解度DMF: 10 mg/ml; DMSO: 12 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 200 μg/ml
酸度系數(shù)(pKa)3.59±0.10(Predicted)
形態(tài)A crystalline solid
顏色White to off-white
常見問(wèn)題列表
生物活性
N-Oleoyl glycine 是一種脂氨酸，在 3T3-L1 脂肪細(xì)胞中，能夠通過(guò)激活 CB1 受體和 Akt 信號(hào)通路來(lái)刺激脂肪形成。靶點(diǎn)
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Human Endogenous Metabolite
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CB1
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Akt
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體外研究
N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. N-Oleoyl glycine (1, 5, 10, 20, 50 μM) dose- and time-dependently stimulates 3T3-L1 adipogenesis after treatment for 1-10 days via activation of CB1R. N-Oleoyl glycine also elevates Akt signaling pathway during the differentiation of 3T3-L1 adipocytes.