25913-34-2
基本信息
鹽酸替諾立定雜質(zhì)
2-氨基-6-芐基-4,5,6,7-四氫噻吩并[2,3-C]吡啶-3-甲酸乙酯鹽酸鹽
Nonflamin
Tinoridine HCl
Einecs 247-342-9
Y-3642 hydrochloride
Tinoridine Hydrochloride
Tenolinidine hydrochloride
Tenocyclidine hydrochloride
Tinoridine Hydrochloride USP/EP/BP
Tenoridine Hydrochloride Impurities
物理化學(xué)性質(zhì)
報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
2024/11/08 | HY-111354 | 鹽酸替諾立定 Tinoridine hydrochloride | 25913-34-2 | 5mg | 750元 |
2024/11/08 | HY-111354 | 鹽酸替諾立定 Tinoridine hydrochloride | 25913-34-2 | 10mM * 1mLin DMSO | 825元 |
2024/11/08 | HY-111354 | 鹽酸替諾立定 Tinoridine hydrochloride | 25913-34-2 | 10mg | 1120元 |
常見問題列表
Tinoridine reduces a stable free radical, diphenyl-p-picrylhydrazyl, in the molar ratio of about 1:2, indicating its free radical scavenging ability. Tinoridine inhibits the lipid peroxidation in rat liver microsomes induced by xanthine-xanthine oxidase system in the presence of ADP and Fe 2+ , in which hydroxyl radical is formed. Tinoridine is demonstrated to be oxidized in the course of the lipid peroxidation by following the fluorescence derived from the oxidation product of tinoridine. It is also oxidized by the xanthine-xanthine oxidase system in the presence of Fe 2+ , but its oxidation is slow in the absence of Fe 2+ and almost completely inhibited by catalase. Tinoridine is also oxidized by H 2 O 2 -Fe 2+ system producing OH (Fenton reaction), but it does not affect the reduction of cytochrome c caused by superoxide radical.
CCl 4 aministration produces a marked decrease in the concentrations of liver microsomal cytochrome P-450 and G6Pase, indicating that hepatic endoplasmic reticulum function is disrupted. Prior treatment of the animals with tinoridine (100 mg/kg) significantly reduces the CCl 4 -induced alterations in the enzyme activities, and a rapid recovery toward the normal values is observed.