2507-24-6
2507-24-6 結(jié)構(gòu)式
基本信息
中文別名
泡蛙肽PHYSALAEMIN肽
英文別名
FI 6422Physalemin
PHYSALAEMIN
Physalaemine
PHYSALAEMIN ACOH 3H2O
Physalemin(7CI,8CI,9CI)
Physalaemin, ≥97% (HPLC)
GLP-ALA-ASP-PRO-ASN-LYS-PHE-TYR-GLY-LEU-MET-NH2
PYR-ALA-ASP-PRO-ASN-LYS-PHE-TYR-GLY-LEU-MET-NH2
PGLU-ALA-ASP-PRO-ASN-LYS-PHE-TYR-GLY-LEU-MET-NH2
所屬類別
生物化工：多肽常見問題列表
用途
Physalaemin最初是從Physalaemus frog中分離出來的，是一種與P物質(zhì)密切相關(guān)的速激肽。它是一種有效的血管擴(kuò)張劑，具有降壓作用。
生物活性
Physalaemin是一種非哺乳動(dòng)物類的速激肽，選擇性地高親和力結(jié)合到神經(jīng)激肽-1 (NK1) 受體。靶點(diǎn)
Neurokinin-1 (NK1) receptor
體外研究
Physalaemin (PHY), an undecapeptide with the sequence pGlu-Ala-Asp-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2, is a member of the tachykinin family of neuropeptides. PHY is very close to the mammalian tachykinin substance P (SP) in its function and chemical composition, and SP is well studied and characterized. Physalaemin is a bradykinin potentiating peptide (BPP-5a).