2375613-31-1
2375613-31-1 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
儲存條件-20°C儲存
溶解度DMF: 20mg/mL; DMF:PBS (pH 7.2) (1:2): 0.3mg/mL; DMSO: 5mg/mL; Ethanol: 12mg/mL
形態(tài)結(jié)晶固體
應(yīng)用領(lǐng)域
用途一
CAY10744 is a topoisomerase II-α poison. It inhibits topoisomerase II-α by 78.9% when used at a concentration of 20 μM. CAY10744 is selective for topoisomerase II-α over topoisomerase I providing 100 and 0% inhibition, respectively, at 100 μM. It inhibits proliferation of HCT15 colon, T47D breast, DU145 prostate, and HeLa cervical cancer cells.