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ChemicalBook--->CAS DataBase List--->2375613-31-1

2375613-31-1

2375613-31-1 Structure

2375613-31-1 Structure
IdentificationBack Directory
[Name]

CAY10744
[CAS]

2375613-31-1
[Synonyms]

CAY10744
[Molecular Formula]

C24H16ClNO2
[MOL File]

2375613-31-1.mol
[Molecular Weight]

385.84
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20mg/mL; DMF:PBS (pH 7.2) (1:2): 0.3mg/mL; DMSO: 5mg/mL; Ethanol: 12mg/mL
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

CAY10744 is a topoisomerase II-α poison. It inhibits topoisomerase II-α by 78.9% when used at a concentration of 20 μM. CAY10744 is selective for topoisomerase II-α over topoisomerase I providing 100 and 0% inhibition, respectively, at 100 μM. It inhibits proliferation of HCT15 colon, T47D breast, DU145 prostate, and HeLa cervical cancer cells.
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