1962928-28-4
中文名稱
二鹽酸LCB 03-0110
英文名稱
LCB 03-0110 dihydrochloride
(LCB03-0110)
CAS
1962928-28-4
分子式
C24H24ClN3O2S
分子量
453.99
MOL 文件
1962928-28-4.mol
1962928-28-4 結構式
應用領域
用途一
LCB 03-0110 dihydrochloride is a potent c-Src kinase inhibitor (IC50 = 1.3 nM). It is also a potent inhibitor of BTK and Syk, discoidin domain receptor 2 (DDR2) family tyrosine kinases. The mechanism of action is it suppresses LPS-induced activation of macrophages and TGF-β1- induced activation of fibroblasts in vitro. LCB 03-0110 dihydrochloride also inhibits activation of macrophages and fibroblasts and suppresses scar formation in a wound healing model.