| Identification | Back Directory | [Name]
LCB 03-0110 dihydrochloride
(LCB03-0110) | [CAS]
1962928-28-4 | [Synonyms]
LCB 03-0110 dihydrochloride
LCB 03-0110 dihydrochloride
(LCB03-0110) | [Molecular Formula]
C24H24ClN3O2S | [MOL File]
1962928-28-4.mol | [Molecular Weight]
453.99 |
| Hazard Information | Back Directory | [Description]
LCB 03-0110 dihydrochloride is a potent c-Src kinase inhibitor (IC50 = 1.3 nM). It is also a potent inhibitor of BTK and Syk, discoidin domain receptor 2 (DDR2) family tyrosine kinases. The mechanism of action is it suppresses LPS-induced activation of macrophages and TGF-β1- induced activation of fibroblasts in vitro. LCB 03-0110 dihydrochloride also inhibits activation of macrophages and fibroblasts and suppresses scar formation in a wound healing model. | [storage]
Desiccate at RT |
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