179411-94-0
中文名稱
(S)-ALPHA-氨基-2'-氯-5-(膦酰甲基)-[1,1'-聯(lián)苯]-3-丙酸單銨鹽
英文名稱
SDZ 220-581 (AMMoniuM salt)
CAS
179411-94-0
分子式
C16H26ClN4O5P
分子量
420.828
MOL 文件
179411-94-0.mol
179411-94-0 結構式
基本信息
中文別名
(S)-ALPHA-氨基-2'-氯-5-(膦酰甲基)-[1,1'-聯(lián)苯]-3-丙酸單銨鹽 英文別名
SDZ 220-581 ammoniumSDZ 220-581 (AMMoniuM salt)
Ammonium (S)-2-amino-3-(2'-chloro-5-(phosphonomethyl)-[1,1'-biphenyl]-3-yl)propanoate
(S)-alpha-Amino-2'-chloro-5-(phosphonomethyl)-[1,1'-biphenyl]-3-propanoic acid monoammonium salt
所屬類別
生物化工：激動劑抑制劑
(S)-ALPHA-氨基-2'-氯-5-(膦酰甲基)-[1,1'-聯(lián)苯]-3-丙酸單銨鹽價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/02/08 | HY-13059A | (S)-ALPHA-氨基-2'-氯-5-(膦酰甲基)-[1,1'-聯(lián)苯]-3-丙酸單銨鹽 SDZ 220-581 Ammonium salt | 179411-94-0 | 5 mg | 550元 |
| 2025/02/08 | HY-13059A | (S)-ALPHA-氨基-2'-氯-5-(膦酰甲基)-[1,1'-聯(lián)苯]-3-丙酸單銨鹽 SDZ 220-581 Ammonium salt | 179411-94-0 | 10mg | 1000元 |
| 2024/04/30 | HY-13059A | (S)-ALPHA-氨基-2'-氯-5-(膦酰甲基)-[1,1'-聯(lián)苯]-3-丙酸單銨鹽 SDZ 220-581 Ammonium salt | 179411-94-0 | 50mg | 5952元 |
常見問題列表
生物活性
SDZ 220-581 Ammonium salt 是一種口服生物利用度，有效的競爭性的 NMDA 受體拮抗劑，pKi 值為 7.7。靶點
pKi: 7.7 ( NMDA receptor )
體內(nèi)研究
SDZ 220-581 (3.2-32 mg/kg; oral administration; for 24 hours; male OF-l mice) treatment dose-dependently protects mice against maximal electroshock seizures (MES). The time-course of protection by SDZ 220-581 is characterized by a rapid onset and long duration of action.
| Animal Model: | Male OF-l mice (18-26 g) |
| Dosage: | 3.2 mg/kg, 10 mg/kg, 32 mg/kg |
| Administration: | Oral administration; for 24 hours |
| Result: | Dose-dependently protected mice against maximal electroshock seizures (MES) upon oral administration. |