1627716-22-6
1627716-22-6 結(jié)構(gòu)式
基本信息
中文別名
化合物 T14910 英文別名
Cd161NKR-P1A
9H-Pyrimido[4,5-b]indole, 7-(3,5-dimethyl-4-isoxazolyl)-6-methoxy-2-methyl-4-(4-quinolinyl)-
應(yīng)用領(lǐng)域
用途一
CD-161 is a potent and orally bioavailable BET inhibitor. CD-161 has excellent microsomal stability and good oral pharmacokinetics in rats and mice. Orally administered, CD-161 achieves significant antitumor activity in the MV4-11 leukemia and MDA-MB-231 triple-negative breast cancer xenograft models in mice.