| Identification | Back Directory | [Name]
Cd161 | [CAS]
1627716-22-6 | [Synonyms]
Cd161
NKR-P1A
9H-Pyrimido[4,5-b]indole, 7-(3,5-dimethyl-4-isoxazolyl)-6-methoxy-2-methyl-4-(4-quinolinyl)- | [Molecular Formula]
C26H21N5O2 | [MDL Number]
MFCD32201066 | [MOL File]
1627716-22-6.mol | [Molecular Weight]
435.48 |
| Hazard Information | Back Directory | [Description]
CD-161 is a potent and orally bioavailable BET inhibitor. CD-161 has excellent microsomal stability and good oral pharmacokinetics in rats and mice. Orally administered, CD-161 achieves significant antitumor activity in the MV4-11 leukemia and MDA-MB-231 triple-negative breast cancer xenograft models in mice. |
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