1621681-63-7
中文名稱
卡博替尼雜質(zhì)DYH
英文名稱
Cabozantinib impurity 1DYH
CAS
1621681-63-7
分子式
C28H24FN3O6
分子量
517.51
MOL 文件
1621681-63-7.mol
更新日期
2024/12/16 10:54:10
1621681-63-7 結(jié)構(gòu)式
基本信息
中文別名
卡博替尼雜質(zhì)04卡博替尼雜質(zhì)DYH
英文別名
Cabozantinib impurity 1DYH4-(4-(1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6,7-dimethoxyquinoline 1-oxide
N-[4-[(6,7-Dimethoxy-1-oxido-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
1,1-Cyclopropanedicarboxamide, N-[4-[(6,7-dimethoxy-1-oxido-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-
所屬類別
分析化學(xué)：藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品應(yīng)用領(lǐng)域
用途一
Cabozantinib N-oxide is a impurity of Cabozantinib (X745500), a medication used to treat medullary thyroid cancer. As well, it can be used in biological study. Computational network biological approach based on pathway cross-talk inhibition identified new synergistic drug combinations using raloxifene and cabozantinib for treatment of human breast cancer in xenograft mouse model. Potent c-MET inhibitor.