1613638-82-6
中文名稱(chēng)
CDK8-IN-4
英文名稱(chēng)
(R)-2-((5-(1H-indazol-5-yl)pyridin-3-yl)amino)-2-phenylethan-1-ol Benzeneethanol, beta-[[5-(1H-indazol-5-yl)-3-pyridinyl]amino]-, (betaR)-
CAS
1613638-82-6
分子式
C20H18N4O
分子量
330.39
MOL 文件
1613638-82-6.mol
1613638-82-6 結(jié)構(gòu)式
基本信息
中文別名
化合物 T17305(R)-2-((5-(1H-吲唑-5-基)吡啶-3-基)氨基)-2-苯基乙醇
英文別名
CDK8-IN-4(R)-2-((5-(1H-indazol-5-yl)pyridin-3-yl)amino)-2-phenylethan-1-ol Benzeneethanol, beta-[[5-(1H-indazol-5-yl)-3-pyridinyl]amino]-, (betaR)-
物理化學(xué)性質(zhì)
沸點(diǎn)631.2±55.0 °C(Predicted)
密度1.329±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)13.20±0.40(Predicted)
形態(tài)Solid
顏色White to light yellow
應(yīng)用領(lǐng)域
用途一
VFN38826, also known as CDK8-IN-4, is a CDK8 inhibitor. VFN38826 was first reported in patent WO2014090692A1, compound example 16, with an IC50 of 0.2 nM. This product has no formal name at the moment.