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ChemicalBook--->CAS DataBase List--->1613638-82-6

1613638-82-6

1613638-82-6 Structure

1613638-82-6 Structure
IdentificationBack Directory
[Name]

(R)-2-((5-(1H-indazol-5-yl)pyridin-3-yl)amino)-2-phenylethan-1-ol Benzeneethanol, beta-[[5-(1H-indazol-5-yl)-3-pyridinyl]amino]-, (betaR)-
[CAS]

1613638-82-6
[Synonyms]

CDK8-IN-4
(R)-2-((5-(1H-indazol-5-yl)pyridin-3-yl)amino)-2-phenylethan-1-ol Benzeneethanol, beta-[[5-(1H-indazol-5-yl)-3-pyridinyl]amino]-, (betaR)-
[Molecular Formula]

C20H18N4O
[MDL Number]

MFCD31657394
[MOL File]

1613638-82-6.mol
[Molecular Weight]

330.39
Chemical PropertiesBack Directory
[Boiling point ]

631.2±55.0 °C(Predicted)
[density ]

1.329±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

13.20±0.40(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Description]

VFN38826, also known as CDK8-IN-4, is a CDK8 inhibitor. VFN38826 was first reported in patent WO2014090692A1, compound example 16, with an IC50 of 0.2 nM. This product has no formal name at the moment.
[Uses]

CDK8-IN-4 is an inhibitor of CDK8 extracted from patent WO2014090692A1, compound example 16, with an IC50 of 0.2 nM.
[References]

[1] Cheng Z, et al. Novel bi-ring phenyl-pyridines/pyrazines for the treatment of cancer. WO2014090692A1
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