1405-97-6
中文名稱(chēng)
短桿菌肽
英文名稱(chēng)
GRAMICIDIN
CAS
1405-97-6
分子式
C99H140N20O17
分子量
1882.29
MOL 文件
1405-97-6.mol
更新日期
2024/12/23 10:30:27
1405-97-6 結(jié)構(gòu)式
基本信息
中文別名
VG-16短桿菌肽 EP標(biāo)準(zhǔn)品
短桿菌肽 USP標(biāo)準(zhǔn)品
GRAMICIDIN (TECHNICAL GRADE)
英文別名
Aids002001GRAMICIDIN
Aids-002001
Gramicidine
GRAMICIDIN D
GRAMACIDIN D
Gramicidinum
GRAMICIDIN,USP
Gramicidin CRS
GramicidinN.F.Xiv
所屬類(lèi)別
原料藥：抗真菌類(lèi)藥物理化學(xué)性質(zhì)
熔點(diǎn)229-230℃
儲(chǔ)存條件2-8°C
溶解度幾乎不溶于水，溶于甲醇，微溶于乙醇
形態(tài)neat
顏色白色至灰白色
水溶解性Soluble in acetic acid and lower alcohols. Practically insoluble in water.
InChIKeyZWCXYZRRTRDGQE-SORVKSEFSA-N
CAS 數(shù)據(jù)庫(kù)1405-97-6
安全數(shù)據(jù)
危險(xiǎn)品標(biāo)志Xn
危險(xiǎn)類(lèi)別碼20/21-36/37/38
安全說(shuō)明26-36-24/25-22
WGK Germany3
RTECS號(hào)MD8225000
海關(guān)編碼2941906000
毒性mouse,LD50,intravenous,1500ug/kg (1.5mg/kg),Science. Vol. 103, Pg. 419, 1946.
常見(jiàn)問(wèn)題列表
生物活性
Gramicidin 是一種抗菌肽，組裝成膜中的通道并增加其對(duì)陽(yáng)離子的滲透性。靶點(diǎn)
Bacterial
體外研究
Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. There is poor Gramicidin activity against E. coli and S. cerevisae as shown from the survival of microbes (%) over a range of Gramicidin concentrations, in contrast with the action of Gramicidin on S. aureus . The microbicidal activity occurs over a range of low Gramicidin and DODAB concentrations which are not toxic to S. cerevisae .