13071-11-9
13071-11-9 結構式
基本信息
(R)-(+)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE
(R)-(+)-1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE
(R)-1-ISOPROPYLAMINO-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE
R-PROPANOLOL
R-(+)-PROPANOLOL HCL
(R)-(+)-PROPANOLOL HYDROCHLORIDE
(R)-(+)-PROPRANOLOL
R-PROPRANOLOL
(R)-(+)-PROPRANOLOL HYDROCHLORIDE
(R)-PROPRANOLOL HYDROCHLORIDE
(R)-[2-hydroxy-3-(naphthyloxy)propyl]isopropylammonium chloride
(R)-(+)-PROPANOLOL HYDROCHLORIDE 99+%
2-Propanol, 1-(1-methylethyl)amino-3-(1-naphthalenyloxy)-, hydrochloride, (2R)-
(+)-Anapriline
2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-, hydrochloride, (+)- (8CI)
2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (2R)- (9CI)
2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (R)-
AY 20694
d-Anapriline
物理化學性質
安全數(shù)據(jù)
應用領域
常見問題列表
鹽酸普奈洛爾為非選擇性β-受體阻斷藥，阻斷心肌的β受體，對β1和β2受體均有拮抗作用。減慢心率，,抑制心臟收縮力與傳導、循環(huán)血量減少、心肌耗氧量降低。
鹽酸普奈洛爾臨床主要用于治療多種原因所致的心律失常，也可用于心絞痛高血壓嗜鉻細胞瘤(手術前準備)等。由于拮抗β2受體可引起支氣管痙攣和哮喘，故本品禁用于支氣管哮喘的病人。
Both isomers of propranolol are capable of preventing adrenaline-induced cardiac arrhythmias in cats anaesthetized with halothane, but the mean dose of (-)-propranolol is 0.09 mg/kg whereas that of (+)-propranolol is 4.2 mg/kg.Both isomers of propranolol are capable of reversing ventricular tachycardia caused by ouabain in anaesthetized cats and dogs. The dose of (-)-propranolol is significantly smaller than that of (+)-propranolol ((R)-Propranolol) in both species.(R)-Propranolol hydrochloride (10 mg/kg) has no antagonistic activity in rats, the cardiac responses to isoprenaline of rat can be blocked by probably much less than 1/100th of that of the (-) isomer in this preparation.