| Identification | Back Directory | [Name]
Heparitin, sulfate | [CAS]
9050-30-0 | [Synonyms]
C00925
Tavidan
Heparitin
Alpha-Idosane
Heparan, sulfate
Heparan N-sulfate
Heparatan sulfate
Heparitin monosulfate
N-Acetylheparan sulfate
Duodenum Heparinoid USP/EP/BP
Heparan Sulphate. Parent polymer for HS Fractions above. | [EINECS(EC#)]
232-939-9 | [Molecular Formula]
C14H23NO21S3 |
| Hazard Information | Back Directory | [Uses]
Heparan Sulfate is a linear polysaccharide in which the backbone is composed of repeating sulfated disaccharide units. Heparan Sulfate is found in the extracellular matrix and on the surfaces of animal cells. It has numerous important biological activities associated with its interaction with diverse proteins. Heparan is used as an anticoagulant drug. | [Definition]
ChEBI: A linear polysaccharide in which the backbone consists of a variably sulfated repeating disaccharide unit. | [in vivo]
Digestion of heparan sulfate impairs context discrimination in a fear conditioning paradigm and oscillatory network activity in the low theta band after fear conditioning. Thus, heparan sulfate maintains neuronal excitability and, as a consequence, support synaptic plasticity and learning[4]. FGF-2/FGFR system is involved in the regulation of astrocytic reactivity and/or proliferation in the brain and its action is potentiated by heparan sulfate[5]. | [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C |
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