| Identification | Back Directory | [Name]
Zein | [CAS]
9010-66-6 | [Synonyms]
ZEIN
Zeins
ZEIN,NF
ZEIN,CORN
Zeintech.
232-722-9
Zein maize
ZEIN (TECHN)
ZEIN FROM CORN
Zein, purified
ZEIN FROM MAIZE | [EINECS(EC#)]
232-722-9 | [Molecular Formula]
N/A | [MDL Number]
MFCD00062414 |
| Chemical Properties | Back Directory | [Appearance]
yellow powder | [Melting point ]
266-283°C | [density ]
1.226 (25C) | [solubility ]
Practically insoluble in acetone, ethanol, and water;
soluble in aqueous alcohol solutions, aqueous acetone solutions
(60–80% v/v), and glycols. Also soluble in aqueous alkaline
solutions of pH 11.5 and above. | [form ]
powder to crystal | [color ]
White to Yellow to Orange | [Merck ]
10119 | [Uses]
Zein is a corn protein produced from corn gluten meal. it lacks the
amino acids, lysine and tryptophan, so it is not suitable as a sole
source of dietary protein. it is insoluble in water and alcohols but is
soluble in aqueous alcohols, glycols, and glycol ethers. it functions
as a film and coating to provide a moisture barrier for nuts and grain
products. it also functions as a coating for confections and a glaze
for panned goods. | [CAS DataBase Reference]
9010-66-6 | [EPA Substance Registry System]
Zeins(9010-66-6) |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow powder | [Definition]
Zein is a protein derived from Zea mays, Gramineae. It belongs to the prolamine class and contains seventeen amino acids. | [Production Methods]
Zein is extracted from corn gluten meal with dilute propan-2-ol. | [General Description]
Zein is a prolamine and an alcohol soluble protein present in maize endosperm cells. Zein is a 20kDa structural protein and is encoded by the gene mapped on the short arm of maize chromosome 7. This protein lacks essential amino acids, such as lysine and tryptophan. Therefore, it has a poor nutritional value. | [Pharmaceutical Applications]
Zein is used as a tablet binder in wet-granulation processes or as a
tablet-coating agent mainly as a replacement for shellac. It is used
primarily as an enteric-coating agent or in extended-release oral
tablet formulations and other delivery systems. Zein is also used
in food applications as a coating agent. | [Biochem/physiol Actions]
Zein is used in the manufacture of fiber, adhesive, coating, ceramic, ink, cosmetic, textile, chewing gum and biodegradable plastics. This protein is a biodegradable and sustainable agropolymer. Thus, it is a great potential replacement for traditional oil-based plastics. | [Safety]
Zein is used in oral pharmaceutical formulations and food
products, and is generally regarded as an essentially nontoxic and
nonirritant material at the levels employed as an excipient.
However, it may be harmful if ingested in large quantities. | [Solubility in organics]
Aqueous alcohols, DMF, glycols, 90% ethanol | [storage]
Zein should be stored in an airtight container, in a cool, dry place. It
has not been reported to polymerize. | [Incompatibilities]
Incompatible with oxidizing agents. | [Regulatory Status]
GRAS listed. Included in the FDA Inactive Ingredients Database
(oral tablets). Included in nonparenteral medicines licensed in the
UK. Included in the Canadian List of Acceptable Non-medicinal
Ingredients. |
| Safety Data | Back Directory | [Safety Statements ]
22-24/25 | [WGK Germany ]
3
| [F ]
21 | [HS Code ]
35040090 | [Safety Profile]
When heated to
decomposition it emits acrid smoke and
irritating fumes. |
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