Identification | Back Directory | [Name]
(2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid | [CAS]
87421-23-6 | [Synonyms]
D-THREO-HYDROXYLEUCINE (2R,3S)-β-Hydroxyleucine (3S)-3-Hydroxy-D-leucine (2R,3S)-b-Hydroxyleucine (2R,3S)-3-Hydroxyleucine threo-3-Hydroxy-D-leucine d(-)-threo-3-hydroxyleucine (2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid (2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid,99.5+%,99+% ee (2R,3S)-(-)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID, 99+% E.E., 99.5+% | [Molecular Formula]
C6H13NO3 | [MOL File]
87421-23-6.mol | [Molecular Weight]
147.17 |
Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
205 °C | [alpha ]
-19.4 º (c=2, 6N HCl 25 ºC) | [Boiling point ]
267.28°C (rough estimate) | [density ]
1.2006 (rough estimate) | [refractive index ]
1.4240 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [Water Solubility ]
soluble |
Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Uses]
(2R,3S)-β-Hydroxyleucine is a nonprotein amino acid. (2R,3S)-β-Hydroxyleucineis an inhibitor of serine protease. In particular, (2R,3S)-β-Hydroxyleucine was effective in inhibiting trypsin and proteinase K of the serine proteases group. (2R,3S)-β-Hydroxyleucine was not able to inhibit the growth of gram-positive and gram-negative bacteria and yeasts unlike its (2S,3R)-isomer. |
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