| Identification | Back Directory | [Name]
AKT Kinase Inhibitor | [CAS]
842148-40-7 | [Synonyms]
3-[2-(4-amino-1
5-c]pyridin-4-yl]-
AKT Kinase Inhibitor
AKT Kinase Inhibitor USP/EP/BP
5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4
3-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-propyn-1-ol
2-Propyn-1-ol, 3-[2-(4-aMino-1,2,5-oxadiazol-3-yl)-7-(3-aMinopropoxy)-1-ethyl-1H-iMidazo[4,5-c]pyridin-4-yl]-
AKT Kinase Inhibitor
(2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-) | [Molecular Formula]
C16H19N7O3 | [MOL File]
842148-40-7.mol | [Molecular Weight]
357.37 |
| Chemical Properties | Back Directory | [Boiling point ]
678.8±65.0 °C(Predicted) | [density ]
1.50 | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 16.67 mg/mL (46.65 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) | [form ]
Powder | [pka]
12.98±0.10(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity. | [in vivo]
Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus. | [target]
| [storage]
Store at -20°C |
|
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
|