| Identification | More | [Name]
Rhodamine B | [CAS]
81-88-9 | [Synonyms]
2-[6-(DIETHYLAMINO)-3-(DIETHYLIMINO)-3H-XANTHEN-9-YL]BENZOIC ACID
9-(2-carboxyphenyl)-3,6-bis(diethylamino)xanthylium chloride
[9-(O-CARBOXYPHENYL)-6-(DIETHYLAMINO)-3H-XANTHEN-3-YLIDENE] DIETHYL-AMMONIUM CHLORIDE
(9-(O-CARBOXYPHENYL)-6-(DIETHYL-AMINO)-3H-XANTHENE-3-YLIDENE)DIETHYL AMMONIUM CHLORIDE
ACID RHODAMINE B
BASIC VIOLET 10
BRILLIANT PINK
BRILLIANT PINK B
BRILLIANT RHODAMINE B
CALCOZINE RHODAMINE BX
CI 45170
CI NO 45170
CI NO 5170
LABOTEST-BB LT00772274
RHODAMIN B
RHODAMINE
RHODAMINE B
RHODAMINE B500
RHODAMINE B CHLORIDE
RHODAMINE B, O | [EINECS(EC#)]
201-383-9 | [Molecular Formula]
C28H31ClN2O3 | [MDL Number]
MFCD00011931 | [Molecular Weight]
479.01 | [MOL File]
81-88-9.mol |
| Chemical Properties | Back Directory | [Appearance]
C.I. Food red 15 is a green crystalline or redviolet powdered solid | [Melting point ]
210-211 (dec.)(lit.)
| [density ]
0.79 g/mL at 20 °C
| [refractive index ]
1.6500 (estimate) | [Fp ]
12 °C | [storage temp. ]
Store at RT. | [solubility ]
H2O: soluble1mg/mL | [Colour Index ]
45170 | [form ]
Solid | [color ]
Green | [PH]
3-4 (10g/l, H2O, 20℃) | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
SOLUBLE | [Merck ]
14,8183 | [BRN ]
4119648 | [LogP]
1.9-2 | [CAS DataBase Reference]
81-88-9(CAS DataBase Reference) | [IARC]
3 (Vol. 16, Sup 7) 1987 | [NIST Chemistry Reference]
Rhodamine b(81-88-9) | [EPA Substance Registry System]
81-88-9(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi,F | [Risk Statements ]
R22:Harmful if swallowed.
R41:Risk of serious damage to eyes.
R68:Possible risk of irreversible effects.
R67:Vapors may cause drowsiness and dizziness.
R36:Irritating to the eyes.
R11:Highly Flammable.
R40:Limited evidence of a carcinogenic effect.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S7:Keep container tightly closed .
S16:Keep away from sources of ignition-No smoking .
S24/25:Avoid contact with skin and eyes .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S39:Wear eye/face protection .
S36:Wear suitable protective clothing .
S22:Do not breathe dust . | [RIDADR ]
UN 3077 9/PG 3
| [WGK Germany ]
3
| [RTECS ]
BP3675000
| [TSCA ]
Yes | [HS Code ]
32041300 | [Hazardous Substances Data]
81-88-9(Hazardous Substances Data) | [Toxicity]
LD50 i.v. in rats: 89.5 mg/kg (Webb) |
| Hazard Information | Back Directory | [General Description]
Green crystals or reddish-violet powder. Used as a dye, especially for paper, as a metal chelating reagent, and in drugs and cosmetics. | [Reactivity Profile]
Acidic organic/inorganic salts, such as C.I. FOOD RED 15(81-88-9), are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions. | [Air & Water Reactions]
Very soluble in water. Solution is bluish-red. Dilute solutions are strongly fluorescent. | [Hazard]
Questionable carcinogen.
| [Potential Exposure]
It is used as a color additive in drugs, foods, cosmetics, and fabric dyes. It is also used as a tracing agent in water pollution studies. May be used as an agricultural chemical | [First aid]
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek Medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a Medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. | [Shipping]
UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. | [Incompatibilities]
Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, strong reducing agents | [Description]
C.I. Food red 15 is a green crystalline or redviolet powdered solid. Molecular weight =479.1. HazardIdentification (based on NFPA-704 M Rating System):Health 1, Flammability 1, Reactivity 0. Highly soluble inwater. | [Chemical Properties]
C.I. Food red 15 is a green crystalline or redviolet powdered solid | [Chemical Properties]
red/brown or green crystals | [Uses]
A useful fluorochrome for histology, FRET and mitochondrial probe. | [Uses]
As a dye, especially for paper; as a reagent for antimony, bismuth, cobalt, niobium, gold, manganese, mercury, molybdenum, tantalum, thallium, tungsten; as biological stain. Provisionally listed for use in drugs and cosmetics. | [Uses]
Rhodamine B is used in biological studies for an anti-reactive oxygen species/hepatic fibrosis drug delivery system based on salvianolic acid B loaded mesoporous silica nanoparticles. Dyes and metabolites, Environmental Testing. | [Definition]
ChEBI: An organic chloride salt having N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethylethanaminium as the counterion. An amphoteric dye commonly used as a fluorochrome. | [storage]
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with C.I. Foodred 15 you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from oxidizers and reducing agents.Where possible, automatically pump liquid from drums orother storage containers to process containers. | [Properties and Applications]
|
TEST ITEMS
|
SPECIFICATION
|
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APPEARANCE
|
GREEN GLITTERY CRYSTAL
|
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SHADE (COMPARE TO STANDARD)
|
CLOSE
|
|
WATER SOLUBILITY (60°C)
|
8 g/L min
|
|
WATER INSOLUBLE
|
0.5% max
|
|
TINTING STRENGTH
|
500-505 %
|
| [Purification Methods]
Major impurities are partially dealkylated compounds not removed by recrystallisation.Purify the dye by chromatography, using ethyl acetate/isopropanol/ammonia (conc)(9:7:4, RF 0.75 on Kieselgel G). It has also been crystallised from a concentrated solution in MeOH by slow addition of dry diethyl ether; or from EtOH containing a drop of conc HCl by slow addition of ten volumes of dry diethyl ether. The solid is washed with ether and air dried. The dried material has also been extracted with *benzene to remove oil-soluble material prior to recrystallisation. Store it in the dark. [Beilstein 18 II 486, 18 III/IV 8246, 19/8 V 669.] |
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