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ChemicalBook--->CAS DataBase List--->80286-58-4

80286-58-4

80286-58-4 Structure

80286-58-4 Structure
IdentificationBack Directory
[Name]

artemisic acid
[CAS]

80286-58-4
[Synonyms]

Qinghao acid
Qing Hau acid
Artemisia Acid
artemisic acid
Artimisinic Acid
ARTEMISININIC ACID
(+)-artemisinicaci
4,11(13)-Cadinadien-12-oic acid
4,11(13)-AMorphadien-12-oic acid
Dihydroartemisinic Artemisic Acid
2-[[(1R)-4β,7-Dimethyl-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalen]-1α-yl]acrylic acid
2-((1R,4R,4aS,8aR)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl)acrylic acid
2-[(1R,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]prop-2-enoic acid
1-Naphthaleneaceticacid, 1,2,3,4,4a,5,6,8a-octahydro-4,7-dimethyl-a-methylene-, (1R,4R,4aS,8aR)-
1-Naphthaleneacetic acid, 1,2,3,4,4a,5,6,8a-octahydro-4,7-dimethyl-α-methylene-, (1R,4R,4aS,8aR)-
[Molecular Formula]

C15H22O2
[MDL Number]

MFCD00238540
[MOL File]

80286-58-4.mol
[Molecular Weight]

234.337
Chemical PropertiesBack Directory
[Melting point ]

129-131℃
[Boiling point ]

373.6±11.0 °C(Predicted)
[density ]

1.019
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

4.32±0.11(Predicted)
[color ]

White to Pale Yellow
[LogP]

5.086 (est)
Hazard InformationBack Directory
[Uses]

Artemisic Acid is a derivative of Artemisinin (A777500), an antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.
[Definition]

ChEBI: A monocarboxylic acid that is prop-2-enoic acid which is substituted at position 2 by a 4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group (the 1S,4R,4aS,8aR diastereoisomer). I is a sesquiterpenoid precursor of artemisinin, obtained from sweet wormwood, Artemisia annua.
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