| Identification | Back Directory | [Name]
Soybean oil, hydrogenated | [CAS]
8016-70-4 | [Synonyms]
HYDROGENATEDSOYOIL
HYDROGENATEDSOYAFAT
HYDROGENATEDSOYAOIL
Sojabohnenoel, hydriert
HYDROGENATEDSOYABEANOIL
HYDROGENATED SOYBEAN OIL
Soybean oil, hydrogenated
Soya bean oil, hydrogenated
FULLYHYDROGENATEDSOYABEANOIL
HIGHLYHYDROGENATEDSOYBEANOIL
PARTIALLYHYDROGENATEDSOYBEANOIL
Soya bean glyceride, hydrogenated
Soybean oil, hydrogenated ISO 9001：2015 REACH | [EINECS(EC#)]
232-410-2 |
| Chemical Properties | Back Directory | [Appearance]
White or almost white mass or powder which melts to a clear, pale yellow liquid when heated. | [solubility ]
Practically insoluble in water, freely soluble in methylene chloride, in light petroleum (bp: 65-70 °C) after heating and in toluene, very slightly soluble in ethanol (96 per cent). | [Uses]
Excipient. | [EPA Substance Registry System]
Hydrogenated soybean oil (8016-70-4) |
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white mass or powder which melts to a clear, pale yellow liquid when heated. | [Production Methods]
Hydrogenated vegetable oil type I is prepared from refined
vegetable oils, which are hydrogenated using a catalyst. | [Pharmaceutical Applications]
Hydrogenated vegetable oil type I may be used as a lubricant in
tablet and capsule formulations. In this application it is used at
concentrations of 1–6% w/w, usually in combination with talc,
silica or a silicate to prevent sticking to tablet punch faces. It may
also be used as an auxiliary binder in tablet formulations.
Hydrogenated vegetable oil type I is additionally used as the
matrix-forming material in lipophilic-based controlled-release
formulations; it may also be used as a coating aid in
controlled-release formulations. It has also been investigated in
hydrophobic melt agglomeration.
Other uses of hydrogenated vegetable oil type I include use as a
viscosity modifier in the preparation of oil-based liquid and
semisolid formulations; in the preparation of suppositories, to
reduce the sedimentation of suspended components and to improve
the solidification process; and in the formulation of liquid and
semisolid fills for hard gelatin capsules.
Fully hydrogenated vegetable oil products may also be used as
alternatives to hard waxes in cosmetics and topical pharmaceutical
formulations. | [Safety]
Hydrogenated vegetable oil type I is used in food products and oral
pharmaceutical formulations, and is generally regarded as a
nontoxic and nonirritant excipient. | [storage]
Hydrogenated vegetable oil type I is a stable material; typically it is
assigned a 2-year shelf-life.
The bulk material should be stored in a well-closed container in a
cool, dry place. | [Incompatibilities]
Incompatible with strong oxidizing agents. | [Regulatory Status]
GRAS listed. Included in the FDA Inactive Ingredients Database
(oral capsules and tablets; rectal and vaginal suppositories and
topical preparations). Included in nonparenteral medicines licensed
in the UK. Included in the Canadian List of Acceptable Nonmedicinal
Ingredients. |
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