| Identification | More | [Name]
7-Ethylcamptothecin | [CAS]
78287-27-1 | [Synonyms]
7-ETHYL-CAMPTOTHECIN,HPLC 99%
(S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
(4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
SN 22
7-Etyl-camptothecin
(4S)-4,11-Diethyl-4-hydroxy-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione | [Molecular Formula]
C22H20N2O4 | [MDL Number]
29349990 | [Molecular Weight]
376.4 | [MOL File]
78287-27-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Light Pink Solid | [Melting point ]
236-241°C | [Boiling point ]
752.9±60.0 °C(Predicted) | [density ]
1.43 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Chloroform and Methanol Mixture (Slightly, Heated, Sonicated), DMSO (Slightly, Heated) | [form ]
Solid | [pka]
11.24±0.20(Predicted) | [color ]
Pale Yellow to Light Orange | [Usage]
An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. | [InChIKey]
MYQKIWCVEPUPIL-JOCHJYFZSA-N | [CAS DataBase Reference]
78287-27-1(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Light Pink Solid | [Uses]
An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. | [Uses]
An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. Irinotecan USP Related Compound E. | [Definition]
ChEBI: 7-ethylcamptothecin is a pyranoindolizinoquinoline. | [Biological Activity]
7-Ethylcamptothecin is one of the camptothecin analogs. Camptothecin (CPT), a cytotoxic alkaloid isolated from camptothecin analogues, has strong antitumor activity against L1210 leukemia and Walker 256 carcinosarcoma models. |
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