| Identification | More | [Name]
N-Methoxy-N-methylacetamide | [CAS]
78191-00-1 | [Synonyms]
N-ACETYL-N,O-DIMETHYLHYDROXYLAMINE
N-METHOXY-N-METHYLACETAMIDE
N-METHOXY-N-METHLACETAMIDE
N-Methoxy-N-methylacetamide, 98 %
N-Methyl-N-methoxyacetamide | [EINECS(EC#)]
628-920-3 | [Molecular Formula]
C4H9NO2 | [MDL Number]
MFCD00060098 | [Molecular Weight]
103.12 | [MOL File]
78191-00-1.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless liquid | [Boiling point ]
152 °C (lit.) | [density ]
0.97 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.426(lit.)
| [Fp ]
121 °F
| [storage temp. ]
Flammables area | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Liquid | [color ]
Colorless | [Water Solubility ]
Soluble | [CAS DataBase Reference]
78191-00-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Risk Statements ]
R10:Flammable. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29280000 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless liquid | [Uses]
N-Methoxy-N-methylacetamide, is a Weinreb amide used in the synthesis of marine natural products myriaporone and usneoidone as a ketone synthon. | [Preparation]
N-Methoxy-N-methylacetamide can be prepared by reaction of Acetyl Chloride with commercially available N,O-Dimethylhydroxylamine hydrochloride in pyridine, followed by distillation at reduced pressure (65%). | [General Description]
Simple Weinreb amide used in the synthesis of marine natural products myriaporone and usneoidone as a ketone synthon. | [storage]
N-Methoxy-N-methylacetamide is stable but should be protected from moisture; use in a fume hood. |
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