| Identification | Back Directory | [Name]
AC-DELTA-ENDORPHIN (HUMAN) | [CAS]
76622-84-9 | [Synonyms]
fragment1-27
d-Endorphin (huMan)
Acetyl, b-Endorphin
Δ-ENDORPHIN (HUMAN)
1-27-β-Endorphin (human)
B-endorphin fragment 1-27
β-Endorphin (1-27), human
AC-DELTA-ENDORPHIN (HUMAN)
BETA-ENDORPHIN, FRAGMENT 1-27
β-endorphin human fragment 1-27
B-ENDORPHIN FRAGMENT 1-27, HUMAN
beta-endorphin, human, fragment 1-27
ACETYL, BETA-ENDORPHIN (1-27), HUMAN
1-27-β-Endorphin (sheep), 27-L-tyrosine-
b-Lipotropin (59-85) (huMan), b-Endorphin (1-27) (huMan), Lipotropin C' FragMent (huMan)
δ-Endorphin (huMan) β-Lipotropin (59-85) (huMan), β-Endorphin (1-27) (huMan), Lipotropin C' FragMent (huMan)
δ-Endorphin (huMan)
β-Lipotropin (59-85) (huMan), β-Endorphin (1-27) (huMan), Lipotropin C' FragMent (huMan)
H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-OH
ACETYL-TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU-PHE-LYS-ASN-ALA-ILE-ILE-LYS-ASN-ALA-TYR-OH | [Molecular Formula]
C139H217N33O40S | [MDL Number]
MFCD00076389 | [MOL File]
76622-84-9.mol | [Molecular Weight]
3022.47 |
| Hazard Information | Back Directory | [Uses]
β-Endorphin (1-27) (human) is an opioid antagonist that binds μ-, δ-, and κ-opioid receptors with Kis of 5.31, 6.17, and 39.82 nM, respectively. β-Endorphin (1-27) (human) inhibits β-Endorphin (HY-P1502)-induced and etorphine-induced analgesia[1][2]. | [References]
[1] Mansour A, et al. The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores. Brain Res. 1995 Nov 27;700(1-2):89-98. DOI:10.1016/0006-8993(95)00928-j
[2] Nicolas P, et al. Beta-endorphin-(1-27) is a naturally occurring antagonist to etorphine-induced analgesia. Proc Natl Acad Sci U S A. 1985 May;82(10):3178-81. DOI:10.1073/pnas.82.10.3178 |
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