Identification | Back Directory | [Name]
2'-(4-METHYLUMBELLIFERYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID SODIUM SALT | [CAS]
76204-02-9 | [Synonyms]
NEU5AC-A-4MU 4-MU-NANA NA Neu5Ac-α-4MU NEU5AC-ALPHA-4MU SODIUM SALT 2-(4-methylumbelliferyl)-A-D-N-*acetylneuraminic 2-(4-methylumbelliferyl)-α-D-N-*acetylneuraminic 2'-(4-METHYLUMBELLIFERYL)-A-D-N-*ACETYLN EURAMINIC A 4-methylumberiferryl-N-acetyl-alpha-D-neuraminic acid Na 4-MethylumbelliferylN-acetyl-a-D-neuraminicacidsodiumsalt 4-methylumbelliferyl-N-acetyl-alpha-D-neuram.A.so-S.dihy. 4-Methylumbelliferyl N-acetyl-α-D-neuraminic acid sodium salt 4-Methylumbelliferyl-N-acetyl-alpha-D-neuraminic acid sodium salt 2'-(4-METHYLUMBELLIFERYL)-A-D-N-ACETYLNEURAMINIC ACID, SODIUM SALT 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic Acid, Sodium Salt 4-Methylumbelliferyl N-acetyl-a-D-neuraminic acid sodium salt ,97% 2'-(4-METHYLUMBELLIFERYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID SODIUM SALT 4-methylumbelliferyl-n-acetyl-α-d-neuraminic acid sodium salt hydrate 4-Methylumbelliferyl-N-acetyl-a-D-neuraminic acid Sodium salt Dihydrate 2'-(4-METHYLUMBELLIFERYL)-A-D-N-ACETYLNEURAMINIC ACID SODIUM SALT HYDRATE 2'-(4-methylumbelliferyl)-α-d-n-acetylneuraminic acid sodium salt hydrate 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid hydrate sodium salt 2μ-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid hydrate sodium salt 2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid sodium salt hydrate N-Acetyl-2-O-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-alpha-neuraminic acid monosodium salt | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C21H24NNaO11 | [MDL Number]
MFCD00057309 | [MOL File]
76204-02-9.mol | [Molecular Weight]
489.41 |
Chemical Properties | Back Directory | [Appearance]
Off-White to Yellow Solid | [Melting point ]
171°C dec. | [storage temp. ]
−20°C
| [solubility ]
H2O: 50 mg/mL, clear, very slightly yellow
|
Hazard Information | Back Directory | [Chemical Properties]
Off-White to Yellow Solid | [Uses]
This compound has been used for fluorometric assay of neuraminidase as well as fluorescent staining of sialidases in PAGE. | [Uses]
Used as a substrate in a fluorometric assay of neuraminidase. | [Description]
4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases.1 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.2,3,4 | [Biochem/physiol Actions]
Substrate for fluorometric assay of neuraminidase. Used for fluorescent staining of sialidases in PAGE. |
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