| Identification | Back Directory | [Name]
4-chlorokynurenine | [CAS]
75802-84-5 | [Synonyms]
4-chlorokynurenine
Vitamin A Impurity 17 (13-Cis-Retinal)
Benzenebutanoic acid, α,2-diamino-4-chloro-γ-oxo-
2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid | [Molecular Formula]
C10H11ClN2O3 | [MDL Number]
MFCD31561919 | [MOL File]
75802-84-5.mol | [Molecular Weight]
242.66 |
| Chemical Properties | Back Directory | [Melting point ]
>165°C (dec.) | [Boiling point ]
516.3±50.0 °C(Predicted) | [density ]
1.454±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Aqueous Acid (Slightly), DMSO (Sparingly) | [form ]
Solid | [pka]
2.13±0.23(Predicted) | [color ]
Pale Yellow to Yellow |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of the NMDA/glycine receptor but penetrates poorly through the blood-brain barrier. ?Its prodrug, L-4-Cl-kynurenine (4-Cl-KYN), readily enters the brain from the circulation and provides antiexcitotoxic neuroprotection after systemic application. |
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