Identification | Back Directory | [Name]
oxycinchophen | [CAS]
485-89-2 | [Synonyms]
Oxinofen Fenidrone Magnofenyl Magnophenyl oxycinchophen | [EINECS(EC#)]
207-624-4 | [Molecular Formula]
C16H11NO3 | [MDL Number]
MFCD00023966 | [MOL File]
485-89-2.mol | [Molecular Weight]
265.267 |
Chemical Properties | Back Directory | [Melting point ]
206.5°C (rough estimate) | [Boiling point ]
408.48°C (rough estimate) | [density ]
1.1861 (rough estimate) | [refractive index ]
1.5300 (estimate) | [storage temp. ]
2-8°C | [pka]
0.55±0.10(Predicted) | [color ]
Minute, deep yellow prisms from alc |
Hazard Information | Back Directory | [Uses]
Oxicinchophen has bene used to study P-selectin antagonistic activity, DHOD inhibitory activity, SAR of quinoline salicylic acids using Pfitzinger reaction of isatin derivatives with (acetyloxy)acetophenone derivatives; effect of antiinflammatory drugs on vascular smooth muscle; increase in oxygen consumption in the absence of a phosphate acceptor and to inhibit ATP synthesis in the isolated rat liver mitochondria. | [Definition]
ChEBI: Oxycinchophen is a member of quinolines. | [Safety Profile]
Low toxicity by ingestion and skin contact. When heated to decomposition it emits toxic fumes of NOx. | [Purification Methods]
It is precipitated from alkaline solution on acidification and crystallises from EtOH or AcOH in yellow crystals. [Marshall & Blanchard J Pharmacol 95 186 1949, Beilstein 22 H 245, 22 II 183, 22 III/IV 2383.] |
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