Identification | Back Directory | [Name]
Diethyl malate | [CAS]
7554-12-3 | [Synonyms]
FEMA 2374 DIETHYL MALATE ETHYL-DL-MALATE DIETHYL DL-MALATE Malic acid diethyl DiethylDL-Malate> Diethyl hydroxysuccinate Diethyl 2-hydroxysuccinate DL-MALIC ACID DIETHYL ESTER DL-APPLE ACID DIETHYL ESTER DL-MALIC ACID DIETHYL ESTER 98+% Diethyl DL-Malate Hydroxysuccinic acid diethyl ester hydroxy-butanedioicacidiethylester Hydroxybutanedioic acid diethyl ester 2-hydroxy-butanedioicaciddiethylester Butanedioicacid,hydroxy-,diethylester Butanedioic acid, 2-hydroxy-, 1,4-diethyl ester diethylmalate,hydroxy-butanedioicacid,diethylester DL-Apple Acid Diethyl Ester
DL-Malic Acid Diethyl Ester | [EINECS(EC#)]
231-444-5 | [Molecular Formula]
C8H14O5 | [MDL Number]
MFCD00048556 | [MOL File]
7554-12-3.mol | [Molecular Weight]
190.19 |
Chemical Properties | Back Directory | [Boiling point ]
122-124 °C12 mm Hg(lit.)
| [density ]
1.128 g/mL at 25 °C(lit.)
| [FEMA ]
2374 | DIETHYL MALATE | [refractive index ]
1.4330 to 1.4360 | [Fp ]
185 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Sparingly), Ethyl Acetate (Slightly) | [form ]
clear liquid | [pka]
12.35±0.20(Predicted) | [color ]
Colorless to Light yellow | [Odor]
at 100.00 %. brown sugar sweet wine fruity herbal | [Odor Type]
caramellic | [JECFA Number]
620 | [Dielectric constant]
10.2(18℃) | [LogP]
0.23 | [EPA Substance Registry System]
Butanedioic acid, hydroxy-, diethyl ester(7554-12-3) |
Hazard Information | Back Directory | [Chemical Properties]
Diethyl malate has a fruity odor with a pleasant herbaceous undertone. It is an ester of dicarboxylic acid | [Occurrence]
It exhibits two optically active isomers in addition to the optically inactive form; the most common is the l-isomer; reported present in the cultures of certain fungi (Rhizopus). Reported found in raspberry, cognac, malt whiskey, cider, sherry,
white, red, port, sparkling, rose, strawberry and bilberry wines | [Uses]
Diethyl DL-Malate is used as a reagent in the synthesis of dicarboxylic nitroxyalkylamides and nitroxyalkylimides as anti-ischemic agents. | [Definition]
ChEBI: Diethyl malate is a malate ester obtained by the formal condensation of the two carboxy groups of malic acid with two molecules of ethanol respectively. It has a role as a metabolite. | [Preparation]
The l-isomer can be prepared by esterification of the l-isomer of the acid with alcohol in the presence of HCl. | [Synthesis Reference(s)]
Synthesis, p. 138, 1982 DOI: 10.1055/s-1982-29718 |
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Spectrum Chemical Manufacturing Corp.
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